Aljarad Ziad, Mobayed Bashir Badawi
Department of Gastroenterology, Faculty of Medicine, University of Aleppo, Syria.
Ann Med Surg (Lond). 2021 Oct 16;71:102958. doi: 10.1016/j.amsu.2021.102958. eCollection 2021 Nov.
acute upper gastrointestinal bleeding (UGIB) is a common medical condition that results in substantial morbidity, mortality, and medical care cost. The mortality rate for patients with acute upper gastrointestinal (GI) bleeding is 5-10%, and it has not changed much since 1945, despite the development in medicines, endoscopy, intensive care units (ICU), and surgical management. We conduct this study to observe some of the factors that predict death in these patients.
The Study was conducted at the Internal Medicine Department, Digestive Division, Aleppo University Hospital, between July 2018 and June 2020. The study included all patients with acute upper GI bleeding who were admitted to the digestive division during the study period, or who were admitted by other departments requesting an upper GI endoscopy.
This study involved 234 patients, 137 males (58.55%), 97 females (41.45%).The patients' ages ranged between 17 and 81 years old, and the mean age value ± standard deviation was 57.15 ± 22.89 years old.The number of deaths reached 22, at a rate of 9.40%, 14 male deaths (10.22%), 8 female deaths (8.25%).
in this study we found a moderate inverse relationship between the hemoglobin value at admission and the incidence of death; the lower the hemoglobin value at admission, the higher the probability of patient's death. Also, there is a very significant direct relationship between the number of blood units transfused and the incidence of death, noting that all patients who died had received blood transfusions. Finally, we found a moderate inverse relationship between the arterial blood pressure value at admission and the incidence of death.
急性上消化道出血(UGIB)是一种常见的病症,会导致较高的发病率、死亡率以及医疗费用。急性上消化道(GI)出血患者的死亡率为5%-10%,自1945年以来,尽管药物、内镜检查、重症监护病房(ICU)及外科治疗有所发展,但该死亡率并无太大变化。我们开展这项研究以观察这些患者中一些预测死亡的因素。
该研究于2018年7月至2020年6月在阿勒颇大学医院消化内科进行。研究纳入了在研究期间入住消化科的所有急性上消化道出血患者,以及由其他科室转诊要求进行上消化道内镜检查的患者。
本研究涉及234例患者,其中男性137例(58.55%),女性97例(41.45%)。患者年龄在17至81岁之间,平均年龄值±标准差为57.15±22.89岁。死亡人数达22例,死亡率为9.40%,其中男性死亡14例(10.22%),女性死亡8例(8.25%)。
在本研究中,我们发现入院时血红蛋白值与死亡率之间存在中度负相关;入院时血红蛋白值越低,患者死亡的可能性越高。此外,输注血液单位数与死亡率之间存在非常显著的正相关,需注意所有死亡患者均接受了输血治疗。最后,我们发现入院时动脉血压值与死亡率之间存在中度负相关。