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手部严重痛风石性痛风的手术重建:一种定制方法。

Surgical Reconstruction of Severe Tophaceous Gout in the Hand: A Customized Approach.

作者信息

Galeano Mariarosaria, Colonna Michele R, Pfanner Sandra, Ceruso Massimo

机构信息

Department of Surgery, Plastic Surgery, Messina University Hospital, Messina Italy.

Department of Human Pathology, University of Messina, Messina, Italy.

出版信息

Plast Reconstr Surg Glob Open. 2021 Nov 2;9(11):e3912. doi: 10.1097/GOX.0000000000003912. eCollection 2021 Nov.

Abstract

Tophaceous gout can represent a major problem for hand surgeons when it turns into aggressive nodules, spreading and destroying soft tissue and bone. The combination of ablative and reconstructive surgery may also be complex when the patient refuses amputations and multiple segments are involved. We present a difficult case, where a customized approach, chosen according to the different features of the osteoarticular and tendon involvement of fingers, adopted different solutions for the four affected rays. A patient suffering from severe gout arthritis with osteoarticular destruction in both hands refused amputations and was treated with several reconstructive procedures. After excision of the tophaceous deposits, a long bone autograft, two segmental cement spacers together with distal arthrodeses, and an osteoarticular allograft were used. Functional pinches were maintained in both hands, even at a 13-year follow up, with the allograft preserved and working. On the other hand, significant osteolysis and bone resorption in all the segments that had undergone stabilization was documented, producing extrusion of both cement and distal interphalangeal joint fusion screws. Pre- and postoperation range of motion, visual analogue scale, disabilities of the arm, shoulder, and hand score, and pinch strength tests showed reduced pain and improved function. A review of literature is presented in particular regarding different reconstructive approaches. Combining different techniques in the same hand can lead to successful osteoarticular reconstruction after tophi resection, above all to avoid amputation. However, long-term follow up shows that functional osteoarticular reconstructions seem to be more stable, whereas osteolysis may damage bone grafts used for arthrodesis and produce screw extrusion.

摘要

当痛风石性痛风发展为侵袭性结节,扩散并破坏软组织和骨骼时,对于手外科医生来说可能是一个重大问题。当患者拒绝截肢且多个部位受累时,切除与重建手术的联合也可能很复杂。我们展示了一个具有挑战性的病例,其中根据手指骨关节和肌腱受累的不同特征选择了定制化方法,对四条受累射线采用了不同的解决方案。一名患有严重痛风性关节炎且双手骨关节破坏的患者拒绝截肢,并接受了多次重建手术。在切除痛风石沉积物后,使用了自体长骨移植、两个节段性骨水泥间隔物以及远端关节融合术,还有一个骨关节异体移植。即使在13年的随访中,双手仍保持功能性捏力,异体移植得以保留并发挥作用。另一方面,记录显示所有接受稳定化处理的节段均出现明显的骨质溶解和骨吸收,导致骨水泥和远端指间关节融合螺钉均出现移位。术前和术后的活动范围、视觉模拟评分、上肢、肩部和手部功能障碍评分以及捏力测试均显示疼痛减轻且功能改善。特别针对不同的重建方法进行了文献综述。在同一手部联合使用不同技术可在痛风石切除术后成功进行骨关节重建,尤其是避免截肢。然而,长期随访表明,功能性骨关节重建似乎更稳定,而骨质溶解可能会破坏用于关节融合的骨移植并导致螺钉移位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37bf/8563068/f20af9c4aaf5/gox-9-e3912-g001.jpg

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