Wang Haiqing, Bao Chengbei, Gong Ting, Ji Chao
Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Central Laboratory, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Front Oncol. 2021 Oct 21;11:747123. doi: 10.3389/fonc.2021.747123. eCollection 2021.
Breast carcinoma en cuirasse (CeC) is an extremely rare form of cutaneous metastases of breast cancer, characterized by diffuse sclerodermoid induration of the skin. It may be difficult to distinguish CeC from some skin diseases, including postirradiation morphea, inflammatory breast cancer, radiation dermatitis, and other cutaneous metastases, but it can be easily discerned by histology. Because of the small number of documented cases, the treatment consensus has not been clearly defined. Here, we show a 45-year-old woman with grade III infiltrating ductal carcinoma manifesting as CeC to the chest wall. Early diagnosis and treatment are essential to prevent the catastrophic natural progression of this rare malignancy.
乳房铠甲样癌（CeC）是一种极为罕见的乳腺癌皮肤转移形式，其特征为皮肤弥漫性硬皮病样硬结。可能难以将CeC与某些皮肤疾病区分开来，包括放疗后硬斑病、炎性乳腺癌、放射性皮炎及其他皮肤转移瘤，但通过组织学检查可轻易辨别。由于记录在案的病例数量较少，治疗共识尚未明确界定。在此，我们展示了一名45岁患有III级浸润性导管癌的女性，其表现为胸壁的CeC。早期诊断和治疗对于预防这种罕见恶性肿瘤的灾难性自然进展至关重要。
