Morganroth Pamela A, Dehoratius Danielle, Curry Heather, Elenitsas Rosalie
*Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA; †Department of Dermatology, University of Pennsylvania, Philadelphia, PA; and ‡Department of Radiation Therapy, Paoli Hospital Cancer Center, Paoli, PA.
Am J Dermatopathol. 2013 Oct 4. doi: 10.1097/DAD.0b013e3181cb3fdd.
: Postirradiation morphea is a rare complication of radiation therapy which often presents as an erythematous indurated plaque and may be mistaken for recurrent or metastatic carcinoma. Histologic examination is essential for distinguishing postirradiation morphea from malignant processes and from other types of radiation dermatitis and infectious cellulitis. We report a case of postirradiation morphea and review the postirradiation morphea literature. In addition, we summarize the clinical and histopathologic characteristics of the various forms of postirradiation skin disease, including postirradiation morphea; acute, subacute, and chronic radiation dermatitis; and radiation recall dermatitis.
放疗后硬斑病是放射治疗的一种罕见并发症，常表现为红斑性硬结斑块，可能被误诊为复发性或转移性癌。组织学检查对于区分放疗后硬斑病与恶性病变、其他类型的放射性皮炎和感染性蜂窝织炎至关重要。我们报告一例放疗后硬斑病病例并复习放疗后硬斑病的文献。此外，我们总结了各种形式的放疗后皮肤疾病的临床和组织病理学特征，包括放疗后硬斑病；急性、亚急性和慢性放射性皮炎；以及放射性回忆性皮炎。
