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鹦鹉热衣原体感染致严重肺炎合并妊娠一例报告。

Pregnancy combined with severe pneumonia caused by Chlamydia psittaci infection - a case report.

机构信息

Department of Emergency, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

出版信息

Ginekol Pol. 2021;92(10):743-744. doi: 10.5603/GP.a2021.0184.

Abstract

OBJECTIVE

Chlamydia psittaci (Cps) feeds on gram-negative aerobic cells. Respiratory inhalation of Cps or close contact with infected animals can cause psittacosis in humans. Given its challengeable early diagnosis and rapid progression, misdiagnosis or improper antibacterial drugs may lead to multi-organ dysfunction with a high mortality.

CASE REPORT

A pregnant woman at 29+1 weeks of gestational age had a fever. CT images of the chest showed lamellar consolidations in the inferior lobe of the right lung, light inflammation in the middle lobe of the right lung. Negative results were obtained from multiple times of blood and sputum culture. Next generation sequencing (NGS) results identified that Cps caused severe pneumonia, which was alleviated by specific antibiotic treatment.

CONCLUSION

Cps can cause severe pneumonia in the pregnant woman and be cured through precise antibiotic treatment. NGS is efficient in the rapid identification of pathogens and accurate diagnosis when bacteriological culture fails.

摘要

目的

鹦鹉热衣原体(Cps)以革兰氏阴性需氧细胞为食。人类吸入 Cps 或与受感染的动物密切接触都可能导致鹦鹉热。鉴于其具有挑战性的早期诊断和快速进展,如果误诊或使用不当的抗菌药物,可能会导致多器官功能障碍,死亡率很高。

病例报告

一名 29+1 周妊娠的孕妇发热。胸部 CT 图像显示右肺下叶呈层状实变,右肺中叶轻度炎症。多次血培养和痰培养结果均为阴性。下一代测序(NGS)结果表明 Cps 引起了严重的肺炎,经特定抗生素治疗后得到缓解。

结论

Cps 可导致孕妇发生严重肺炎,通过精确的抗生素治疗可以治愈。当细菌培养失败时,NGS 可快速识别病原体并进行准确诊断,具有较高的效率。

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