Yeak Dieu Siang Justin, Mohamed Mohd Nahar Azmi Bin, Mohd Ramli Norlina Binti, Zahari Mimiwati Binti
37447University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Eur J Ophthalmol. 2022 Jul;32(4):2265-2273. doi: 10.1177/11206721211051236. Epub 2021 Nov 6.
Exercise may potentially provide an adjunctive measure to help control intraocular pressure in glaucoma patients. However, currently, there is still no substantial evidence that regular exercise can produce a prolonged effect of intraocular pressure reduction. We aim to determine the effects of regular exercise on intraocular pressure in healthy individuals.
We conducted a prospective, interventional study at the University of Malaya Medical Centre. Our subjects consist of 45 healthy participants in the intervention arm, and 38 healthy control participants who were age- and gender-matched. The intervention arm was enrolled into a supervised exercise programme for a 6-week period, where controls were asked to continue their usual daily lifestyle. The intervention consists of three sessions every week, which focused on aerobic exercise and strength training.
Baseline intraocular pressure was measured, and then remeasured again at the end of 6 weeks of exercise conditioning. In the intervention group, there was a reduction of baseline intraocular pressure from pre-intervention mean intraocular pressure of 15.55 ± 2.63 mmHg, down to 13.36 ± 3.16 mmHg at 6 weeks, a statistically significant reduction of -2.18 ± 2.25 mmHg ( < 0.001) post-intervention. On the other hand, the control group recorded a non-statistically significant mean increase of 0.63 ± 2.47 mmHg ( = 0.123) at 6 weeks.
Our study concluded that regular exercise results in a significant intraocular pressure reduction in healthy individuals.
运动可能为青光眼患者控制眼压提供辅助措施。然而,目前仍没有充分证据表明规律运动能产生长期降低眼压的效果。我们旨在确定规律运动对健康个体眼压的影响。
我们在马来亚大学医学中心进行了一项前瞻性干预研究。我们的受试者包括干预组的45名健康参与者和38名年龄及性别匹配的健康对照参与者。干预组参加了为期6周的有监督的运动计划,而对照组被要求继续其日常的生活方式。干预包括每周三次课程,重点是有氧运动和力量训练。
测量了基线眼压,然后在6周运动训练结束时再次测量。在干预组中,基线眼压从干预前平均眼压15.55±2.63 mmHg降至6周时的13.36±3.16 mmHg,干预后有统计学意义的降低-2.18±2.25 mmHg(<0.001)。另一方面,对照组在6周时记录到平均升高0.63±2.47 mmHg,无统计学意义(=0.123)。
我们的研究得出结论,规律运动可使健康个体的眼压显著降低。