文献检索，用中文搜 PubMed

To evaluate the inbreeding of yellow-feathered chickens (YFCs) and identify genes related to their unique characteristics, whole-genome re-sequencing data were applied to detect runs of homozygosity (ROH) in the genomes of 10 YFC chickens from each of 10 different YFC breeds. The number, length, distribution of ROH, and inbreeding coefficient in different YFC populations were calculated. Genomic regions with high frequency in ROH were annotated.2. In total, 25,547 ROH with an average length of 335 kb were detected, with most being <1 Mb. The domination of short ROH reflected the long breeding history of this chicken. The number, length, frequency, and distribution of ROH varied among chicken populations, and high genetic diversity was maintained.3. Numerous genes related to YFC characteristics were identified in the high-frequency ROH regions. Among these, , and genes were involved in disease resistance. The , and genes were associated with energy material metabolism; and , and were related to meat quality and flavour. The , and genes, related to pigmentation, were detected.4. This ROH-based inbreeding evaluation lays the foundation for breeding and conservation of YFC populations, and the candidate genes identified can be used for marker-assisted selection.

To evaluate the inbreeding of yellow-feathered chickens (YFCs) and identify genes related to their unique characteristics, whole-genome re-sequencing data were applied to detect runs of homozygosity (ROH) in the genomes of 10 YFC chickens from each of 10 different YFC breeds. The number, length, distribution of ROH, and inbreeding coefficient in different YFC populations were calculated. Genomic regions with high frequency in ROH were annotated.2. In total, 25,547 ROH with an average length of 335 kb were detected, with most being <1 Mb. The domination of short ROH reflected the long breeding history of this chicken. The number, length, frequency, and distribution of ROH varied among chicken populations, and high genetic diversity was maintained.3. Numerous genes related to YFC characteristics were identified in the high-frequency ROH regions. Among these, , and genes were involved in disease resistance. The , and genes were associated with energy material metabolism; and , and were related to meat quality and flavour. The , and genes, related to pigmentation, were detected.4. This ROH-based inbreeding evaluation lays the foundation for breeding and conservation of YFC populations, and the candidate genes identified can be used for marker-assisted selection.

为了评估黄羽肉鸡（YFC）的近交程度并鉴定与其独特特征相关的基因，应用全基因组重测序数据检测了来自 10 个不同 YFC 品种的 10 只 YFC 鸡的基因组中的纯合子区域（ROH）。计算了不同 YFC 群体中 ROH 的数量、长度、分布和近交系数。注释了 ROH 中高频出现的基因组区域。
共检测到 25547 个平均长度为 335kb 的 ROH，大多数<1Mb。短 ROH 的主导反映了这种鸡的悠久繁殖历史。鸡群之间 ROH 的数量、长度、频率和分布存在差异，保持了较高的遗传多样性。
在高频率 ROH 区域中鉴定到了许多与 YFC 特征相关的基因。其中，和基因参与了疾病抗性；和基因与能量物质代谢有关；和基因与肉质和风味有关；和基因与色素沉着有关。
基于 ROH 的近交评估为 YFC 种群的选育和保护奠定了基础，鉴定出的候选基因可用于标记辅助选择。

Suppr 超能文献