Schaad U B
Schweiz Med Wochenschr. 1987 May 30;117(22):845-8.
The different causes of vaccine failure are presented on the basis of epidemiological definitions and facts. The relevant factors necessary for successful active immunization are potential presence of passively transmitted antibodies, possible interaction with combined vaccine administration, technical requirements, individual immune response, and duration of immunity. Knowledge of these factors often provides the individual explanation for vaccine failure, or serves to prevent it as well as to predict susceptibility to natural infection.
根据流行病学定义和事实，介绍了疫苗失效的不同原因。成功进行主动免疫所需的相关因素包括被动传递抗体的潜在存在、与联合疫苗接种的可能相互作用、技术要求、个体免疫反应以及免疫持续时间。了解这些因素通常能为疫苗失效提供个体解释，或有助于预防疫苗失效以及预测对自然感染的易感性。
