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丹麦 2000 年至 2017 年慢性非癌性疼痛患病率的上升:一项基于人群的调查。

Increasing prevalence of chronic non-cancer pain in Denmark from 2000 to 2017: A population-based survey.

机构信息

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Department of Oncology, Rigshospitalet-Copenhagen University Hospital, Copenhagen, Denmark.

出版信息

Eur J Pain. 2022 Mar;26(3):624-633. doi: 10.1002/ejp.1886. Epub 2021 Nov 17.

Abstract

BACKGROUND

This investigation comprised information from the Danish population to analyse the development of chronic non-cancer pain (CNCP) prevalence according to sex, age, physical job demand and educational level.

METHODS

Data derives from the Danish Health and Morbidity Surveys based on random samples of adults living in Denmark. The analysed samples were composed by 10,457 in 2000 (response rate: 62.7%), 5686 in 2005 (52.1%), 15,165 in 2010 (60.1%), 14,265 in 2013 (57.1%) and 14,022 in 2017 (56.1%). CNCP was defined as pain lasting 6 months or more. Individuals with a self-reported history of cancer were excluded. Calibration weighting was applied to reduce the impact of potential non-response bias. The Relative and the Absolute Concentration Index were calculated to measure educational inequalities.

RESULTS

CNCP prevalence has increased 8.3 percentage points during 2000-2017 (19.5%-27.8%) and is highest among women (22.1% to 30.8%). Higher CNCP prevalence among men aged 45-64 years exceeded the men aged >65 years in 2017 (31.9% and 29.8%, respectively). There was a continuous increase in CNCP prevalence in individuals with sedentary work or low physical demand at job from 2000 to 2017; among those with moderate or high physical demand at job the prevalence increased sharply from 2000 to 2010 after which the prevalence remained stable. Higher CNCP prevalence persisted among individuals with lower level of education regardless of gender and the inequalities remained stable over time.

CONCLUSION

The Danish prevalence of chronic pain has increased in the last two decades and higher numbers are observed in some sociodemographic groups.

SIGNIFICANCE

This study provides an overview of the development of chronic non-cancer pain in a country and analyses the trends with socioeconomic inequalities. The continuous increasing prevalence may have huge social and economic implications. This study reveals an urgent need for measures to attenuate the increasing prevalence, which should be a priority for public health policy.

摘要

背景

本研究基于丹麦人群的信息,旨在分析按性别、年龄、体力工作需求和教育水平划分的慢性非癌症疼痛(CNCP)患病率的变化趋势。

方法

数据来源于丹麦健康和发病率调查,基于丹麦成年人的随机样本。分析的样本包括 2000 年的 10457 人(应答率:62.7%)、2005 年的 5686 人(52.1%)、2010 年的 15165 人(60.1%)、2013 年的 14265 人(57.1%)和 2017 年的 14022 人(56.1%)。CNCP 定义为持续 6 个月或更长时间的疼痛。排除有癌症病史的个体。采用校准加权法来降低潜在非应答偏倚的影响。计算相对集中指数和绝对集中指数来衡量教育不平等。

结果

2000 年至 2017 年期间,CNCP 的患病率增加了 8.3 个百分点(19.5%至 27.8%),女性患病率最高(22.1%至 30.8%)。2017 年,45-64 岁男性的 CNCP 患病率高于 65 岁以上男性(分别为 31.9%和 29.8%)。2000 年至 2017 年期间,从事久坐或体力需求低工作的个体中 CNCP 的患病率持续上升;从事中高强度体力工作的个体中,CNCP 的患病率在 2000 年至 2010 年期间急剧上升,此后保持稳定。无论性别如何,教育程度较低的个体中 CNCP 的患病率持续较高,且不平等状况随时间保持稳定。

结论

在过去的二十年中,丹麦慢性疼痛的患病率有所上升,在一些社会人口群体中更为明显。

意义

本研究概述了一个国家慢性非癌症疼痛的发展情况,并分析了与社会经济不平等相关的趋势。患病率的持续上升可能会产生巨大的社会和经济影响。本研究揭示了迫切需要采取措施来减轻不断上升的患病率,这应成为公共卫生政策的优先事项。

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