Department of Health Sciences, Faculty of Human Life and Environment, Nara Women's University, Nara, Japan.
The Elementary School Attached to Nara Women's University, Nara, Japan.
PLoS One. 2021 Nov 8;16(11):e0259653. doi: 10.1371/journal.pone.0259653. eCollection 2021.
We investigated modality differences in the N2 and P3 components of event-related potentials (ERPs) between somatosensory and auditory Go/No-go paradigms in eighteen healthy prepubescent children (mean age: 125.9±4.2 months). We also evaluated the relationship between behavioral responses (reaction time, reaction time variability, and omission and commission error rates) and amplitudes and latencies of N2 and P3 during somatosensory and auditory Go/No-go paradigms. The peak latency of No-go-N2 was significantly shorter than that of Go-N2 during somatosensory paradigms, but not during auditory paradigms. The peak amplitude of P3 was significantly larger during somatosensory than auditory paradigms, and the peak latency of P3 was significantly shorter during somatosensory than auditory paradigms. Correlations between behavioral responses and the P3 component were not found during somatosensory paradigms. On the other hand, in auditory paradigms, correlations were detected between the reaction time and peak amplitude of No-go-P3, and between the reaction time variability and peak latency of No-go-P3. A correlation was noted between commission error and the peak latency of No-go-N2 during somatosensory paradigms. Compared with previous adult studies using both somatosensory and auditory Go/No-go paradigms, the relationships between behavioral responses and ERP components would be weak in prepubescent children. Our data provide findings to advance understanding of the neural development of motor execution and inhibition processing, that is dependent on or independent of the stimulus modality.
我们研究了 18 名健康青春期前儿童（平均年龄：125.9±4.2 个月）在体感和听觉 Go/No-go 范式中事件相关电位（ERPs）的 N2 和 P3 成分的模态差异。我们还评估了行为反应（反应时间、反应时间变异性以及遗漏和错误率）与体感和听觉 Go/No-go 范式中 N2 和 P3 的振幅和潜伏期之间的关系。体感范式中 No-go-N2 的峰值潜伏期明显短于 Go-N2，但听觉范式中则不然。体感范式中 P3 的峰值振幅明显大于听觉范式，而 P3 的峰值潜伏期明显短于听觉范式。体感范式中，行为反应与 P3 成分之间没有相关性。另一方面，在听觉范式中，发现了 No-go-P3 的反应时间和峰值振幅以及 No-go-P3 的反应时间变异性和峰值潜伏期之间的相关性。体感范式中，发现了错误率和 No-go-N2 的峰值潜伏期之间的相关性。与之前使用体感和听觉 Go/No-go 范式的成人研究相比，青春期前儿童的行为反应与 ERP 成分之间的关系较弱。我们的数据为推进对运动执行和抑制处理的神经发育的理解提供了依据，这些理解取决于或独立于刺激模式。
