Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
Department of Emergency Medicine, Kansai Rosai Hospital, Amagasaki, Japan.
Ann Thorac Surg. 2022 Jul;114(1):e21-e24. doi: 10.1016/j.athoracsur.2021.10.003. Epub 2021 Nov 5.
This report describes a case of coronavirus disease 2019 (COVID-19)-associated respiratory failure requiring urgent living-donor lobar lung transplantation (LDLLTx). Severe hypoxia requiring extracorporeal membrane oxygenation (ECMO) developed in a 57-year-old woman with positive viral status. Her respiratory function deteriorated, with almost totally collapsed lungs. All of her other organs functioned well. After 104 days of ECMO support, she underwent urgent LDLLTx using cardiopulmonary bypass. The grafts worked well, and she was weaned from cardiopulmonary bypass after reperfusion. LDLLTx is an option for selected patients with post-COVID-19 end-stage respiratory failure.
本报告描述了一例由 2019 年冠状病毒病（COVID-19）引起的呼吸衰竭，需要紧急进行活体供肺叶移植（LDLLTx）。一名 57 岁女性患者病毒检测呈阳性，出现严重缺氧需要体外膜氧合（ECMO）治疗。她的呼吸功能恶化，肺部几乎完全塌陷。她的其他器官功能良好。在 ECMO 支持 104 天后，她接受了紧急的 LDLLTx 治疗，使用心肺转流。移植物功能良好，再灌注后她成功脱离心肺转流。LDLLTx 是治疗 COVID-19 后终末期呼吸衰竭的一种选择。
