College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, Jilin province, 132101, China.
College of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin province, 130118, China.
Microb Pathog. 2021 Dec;161(Pt B):105268. doi: 10.1016/j.micpath.2021.105268. Epub 2021 Nov 5.
Goat milk is considered as one of the most suitable substitute for human milk, especially for children, the aged and those with cow milk allergies. Consumption of raw or unpasteurized goat milk has been known to be a potential route of Toxoplasma gondii infection for human beings. However, no studies have been carried out to detect T. gondii in goat milk in China. Thus, this stuy was firstly carried out to detect T. gondii IgG antibody in domestic goat's serum and milk during lactation by a commercial validated ELISA kit in China. In total, 10.49% (66/629) serum samples and 9.70% (61/629) milk samples randomly collected from Shandong and Jilin provinces were seropositive for anti-T. gondii IgG, respectively. A high correlation of S/P% value was obtained between serum and milk samples (Spearman's coefficient = 0.891, p-value <0.001 and Kendall's tau = 0.724, p-value < 0.001). Statistical analysis showed that history of abortion, source of water and source of fodder were considered to be highly related to the T. gondii infection in the investigated domestic goats. The present results provide important information for the control and prevention of toxoplasmosis in goats and human beings in China.
羊奶被认为是最适合人类食用的替代母乳之一，尤其适合儿童、老人和牛奶过敏人群。人类食用生羊奶或未经巴氏消毒的羊奶会感染弓形虫。然而，在中国尚未有研究检测羊奶中的弓形虫。因此，本研究首次使用在中国获得验证的商业 ELISA 试剂盒检测哺乳期山羊血清和奶中的弓形虫 IgG 抗体。本研究从山东和吉林两省随机采集了 629 份血清和 629 份奶样，结果显示，血清和奶样中抗弓形虫 IgG 的阳性率分别为 10.49%（66/629）和 9.70%（61/629）。血清和奶样之间的 S/P%值具有高度相关性（Spearman 相关系数=0.891，p 值<0.001；Kendall's tau 相关系数=0.724，p 值<0.001）。统计分析表明，流产史、水源和饲料来源与调查山羊的弓形虫感染高度相关。本研究结果为中国控制和预防山羊和人群的弓形虫病提供了重要信息。
