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打鼾与高血压的相关性:系统评价和荟萃分析。

Association between self-reported snoring and hypertension: a systematic review and meta-analysis.

机构信息

School of Nursing, Jilin University, Changchun, Jilin, 130000, China.

出版信息

Sleep Med. 2021 Dec;88:140-148. doi: 10.1016/j.sleep.2021.10.016. Epub 2021 Oct 23.

Abstract

OBJECTIVES

The purpose of this study is to summarize the evidence for the association between snoring and hypertension and the effect of snoring on hypertension in men and/or women.

METHODS

We searched the articles in the Cochrane Library, PubMed, Scopus, Web of Science and Embase published up to 12 November 2020 to evaluate the association between snoring and hypertension. Studies were selected according to the predefined screening criteria and their qualities were assessed by Newcastle-Ottawa Quality Evaluation Scale. The odds ratio and 95% confidence interval were used as effective indicators. It was registered in PROSPERO with the number: CRD42021224912.

RESULTS

According to the inclusion/exclusion criteria, 11 studies including eight prospective cohort studies and three cross-sectional studies were included. The results showed that compared with non-snoring participants, snoring significantly increased the risk of hypertension in both men and women [odds ratio (OR) = 1.32, 95% confidence interval (CI), 1.23-1.42; men: odds ratio (OR) = 1.32; 95% confidence interval (CI), 1.18-1.49; women: odds ratio (OR) = 1.26; 95% confidence interval (CI), 1.14-1.40]. Besides, the risk of hypertension was significantly increased when the snoring frequency was ≥4 nights/week [frequency≥4 nights/week: odds ratio (OR) = 1.42; 95% confidence interval (CI), 1.21-1.66; 4 nights/week >frequency>0: odds ratio (OR) = 1.23; 95% confidence interval (CI),1.13-1.34].

CONCLUSIONS

Snoring is considered as an independent predictor of hypertension in both men and women, which may play a role in the prevention and control of hypertension. People who snore frequently should pay close attention to their blood pressure levels to prevent hypertension.

摘要

目的

本研究旨在总结打鼾与高血压之间关联的证据,以及打鼾对男性和/或女性高血压的影响。

方法

我们检索了 Cochrane 图书馆、PubMed、Scopus、Web of Science 和 Embase 中截至 2020 年 11 月 12 日发表的评估打鼾与高血压之间关联的文章。根据预先设定的筛选标准选择研究,并使用 Newcastle-Ottawa 质量评估量表评估其质量。使用优势比(OR)和 95%置信区间(CI)作为有效指标。该研究已在 PROSPERO 注册,编号为:CRD42021224912。

结果

根据纳入/排除标准,纳入了 11 项研究,包括 8 项前瞻性队列研究和 3 项横断面研究。结果显示,与不打鼾的参与者相比,打鼾显著增加了男性和女性患高血压的风险[OR=1.32,95%CI(1.23-1.42);男性:OR=1.32;95%CI(1.18-1.49);女性:OR=1.26;95%CI(1.14-1.40)]。此外,当打鼾频率≥4 晚/周时,患高血压的风险显著增加[频率≥4 晚/周:OR=1.42;95%CI(1.21-1.66);4 晚/周>频率>0:OR=1.23;95%CI(1.13-1.34)]。

结论

打鼾被认为是男性和女性高血压的独立预测因素,这可能在高血压的预防和控制中发挥作用。经常打鼾的人应密切关注自己的血压水平,以预防高血压。

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