Wu S S, Ma C N, Zhang L, Duan W, Sun Y, Dou X F, Wang X L, Jia L, Yang P, Wang Q Y, Pang X H
Institute for Infectious Disease and Endemic Disease Control, Beijing Municipal Center for Disease Prevention and Control, Beijing Research Center for Preventive Medicine, Beijing 100013, China.
Office of Global Health Center, Beijing Municipal Center for Disease Prevention and Control, Beijing Research Center for Preventive Medicine, Beijing 100013, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Nov 6;55(11):1311-1315. doi: 10.3760/cma.j.cn112150-20210727-00710.
To investigate the epidemiological characteristics and the chain of infection of a local outbreak, which was the first outbreak caused by severe acute respiratory syndrome corona virus 2 Alpha variant in China and occurred in Daxing district, Beijing. Epidemiological investigation and big data technology were used to verify the exposure points of the cases. Close contacts were traced from the exposure points, and their human and environmental samples were collected for nucleic acid tests. Serum samples were collected from key persons for antibody detection. A total of 33 corona virus disease 2019(COVID-19) cases were reported in the local outbreak, from January 17, 2021 to January 29, 2021 in Daxing district, Beijing, and there was epidemiological association in 32 cases. Except for one case who was infected in the workplace, other cases were all infected in the community and family. All cases involved 14 families, of which 6 families were all infected. The attack rate of all family members was 69%(33/48), and the secondary attack rate was 56%(19/34). There was no obvious source of infection found after the investigation of entry-exit personnel and goods. The first outbreak caused by severe acute respiratory syndrome corona virus 2 Alpha variant in China is found and handled in time, and thus the scope of influence is limited, but the family clustering characteristics are more obvious than previous outbreaks.
为调查一起局部疫情的流行病学特征及感染链条，该疫情是中国首例由严重急性呼吸综合征冠状病毒2阿尔法变异株引起的疫情，发生在北京大兴区。采用流行病学调查和大数据技术核实病例的暴露点。从暴露点追踪密切接触者，并采集其人员和环境样本进行核酸检测。采集重点人员的血清样本进行抗体检测。2021年1月17日至1月29日，北京大兴区局部疫情共报告33例新型冠状病毒肺炎（COVID-19）病例，32例存在流行病学关联。除1例在工作场所感染外，其他病例均在社区和家庭中感染。所有病例涉及14个家庭，其中6个家庭全部感染。所有家庭成员的罹患率为69%（33/48），二代发病率为56%（19/34）。对出入境人员和货物进行调查后未发现明显感染源。中国首例由严重急性呼吸综合征冠状病毒2阿尔法变异株引起的疫情被及时发现并处置，影响范围有限，但家庭聚集性特征比以往疫情更为明显。
