Huang Xing, Deng Hao, Shen Qing-Kun, Quan Zhe-Shan
Key Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Yanji, Jilin, 133002, China.
Curr Med Chem. 2022;29(11):1959-1989. doi: 10.2174/0929867328666211108110025.
Tanshinone IIA, a major bioactive constituent of Danshen, a Chinese herbal medicine, has gained extensive exploration owing to its unique structural features and multiple promising biological activities. This review focuses on the pharmacology, total synthesis, and structural modifications of tanshinone IIA. We hope this review will contribute to a better understanding of the progress in the field and provide constructive suggestions for further study of tanshinone IIA.
丹参酮IIA是一种中药丹参的主要生物活性成分，因其独特的结构特征和多种潜在的生物活性而受到广泛研究。本综述重点关注丹参酮IIA的药理学、全合成及结构修饰。我们希望本综述有助于更好地理解该领域的进展，并为丹参酮IIA的进一步研究提供建设性建议。
