小鼠胸腺中与神经相关的3S乙酰胆碱酯酶

Nerve-related 3S acetylcholinesterase in murine thymus.

作者信息

Bulloch K, Bossone S A

出版信息

Ann N Y Acad Sci. 1987;496:338-45. doi: 10.1111/j.1749-6632.1987.tb35785.x.

DOI:10.1111/j.1749-6632.1987.tb35785.x

Abstract

One form of acetylcholinesterase (AChE), 3S, has been identified in the thymus of normal mice as the predominant species. Histochemical studies show that the AChE is localized to nerves or to nerve-related tissues. The form isolated is composed of a salt and a detergent-sensitive fraction. Since the sedimentation values and the kinetics of the two fractions are identical, it is proposed that only one gene encodes for this globular 3S species of AChE.

摘要

在正常小鼠的胸腺中，已鉴定出乙酰胆碱酯酶（AChE）的一种形式，即3S，它是主要类型。组织化学研究表明，AChE定位于神经或与神经相关的组织。分离出的这种形式由一个盐敏感部分和一个去污剂敏感部分组成。由于这两个部分的沉降值和动力学相同，因此有人提出，只有一个基因编码这种球状3S形式的AChE。