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中国中老年人群代谢综合征的患病率及相关因素:一项全国性横断面研究。

Prevalence and associated factors of metabolic syndrome in Chinese middle-aged and elderly population: a national cross-sectional study.

机构信息

Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.

Department of Urology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Aging Male. 2021 Dec;24(1):148-159. doi: 10.1080/13685538.2021.1998432.

Abstract

BACKGROUND

Currently, China has an increasingly aging population. However, the prevalence of metabolic syndrome (MetS) in this high-risk population for metabolic diseases remains unknown. This study investigates the age- and gender-specific prevalence and associated factors of MetS in the middle-aged and elderly Chinese population.

METHODS

Data were collected and subjected to descriptive statistics. Further, univariate logistic regression was used to evaluate the relevant factors, and then multivariate logistic regression was selected to construct the final model.

RESULTS

A total of 10,834 participants were included in the present study. The overall prevalence of MetS is 32.97% as defined by International Diabetes Federation (IDF) and 29.75% under National Cholesterol Education Program-The Adult Treatment Panel III (NCEP-ATP III) criteria. With aging, the prevalence of MetS descends in males while ascends in females. In the >70 years old group, the prevalence of MetS is three times higher in females than that in males (50.43% versus 16.03%). Across all age groups and sexes, the prevalence of MetS in urban areas is significantly higher than in rural areas. Besides, regardless of gender, the prevalence of MetS is the highest for those living in the north region (28.41% for males and 51.74% for females) and the lowest for those living in the southwest region (13.91% for males and 31.58% for females). Finally, an afternoon nap has been identified as a positively associated factor, while blood urea nitrogen (BUN) has been identified as a negatively associated factor ( < 0.05).

CONCLUSION

The prevalence of MetS varies in different age groups, sexes, living areas, and regions. An afternoon nap is positively associated with the prevalence of MetS, while BUN is negatively associated with MetS.

摘要

背景

目前,中国人口老龄化程度日益加深。然而,代谢综合征(MetS)在这一代谢性疾病高危人群中的流行情况尚不清楚。本研究旨在调查中国中老年人群中代谢综合征的年龄和性别特异性流行情况及其相关因素。

方法

收集数据并进行描述性统计分析。进一步采用单因素 logistic 回归评估相关因素,然后选择多因素 logistic 回归构建最终模型。

结果

本研究共纳入 10834 名参与者。根据国际糖尿病联盟(IDF)标准,MetS 的总体患病率为 32.97%,根据美国国家胆固醇教育计划-成人治疗专家组 III(NCEP-ATP III)标准,患病率为 29.75%。随着年龄的增长,男性 MetS 的患病率下降,而女性则上升。在>70 岁的人群中,女性 MetS 的患病率是男性的三倍(50.43%比 16.03%)。在所有年龄组和性别中,城市地区 MetS 的患病率明显高于农村地区。此外,无论性别如何,北方地区 MetS 的患病率最高(男性为 28.41%,女性为 51.74%),西南地区最低(男性为 13.91%,女性为 31.58%)。最后,午睡被确定为一个正相关因素,而血尿素氮(BUN)被确定为一个负相关因素(<0.05)。

结论

MetS 的患病率在不同年龄组、性别、居住地区和地区之间存在差异。午睡与 MetS 的患病率呈正相关,而 BUN 与 MetS 呈负相关。

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