Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.
Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany; European Virus Bioinformatics Centre, Jena, Germany.
J Hosp Infect. 2022 Feb;120:9-13. doi: 10.1016/j.jhin.2021.10.019. Epub 2021 Nov 6.
The highest viral loads of severe acute respiratory syndrome coronavirus-2 are detectable in the oral cavity, so a potential reduction of infectious virus by nasal and oral sprays could reduce transmission. Therefore, the inactivation capacity of nine nasal and oral sprays was evaluated according to EN 14476. One nasal spray based on sodium hypochlorite and one oral spray containing essential oils reduced viral titres by two to three orders of magnitude. Although clinical data are still sparse, nasal and oral sprays display a more convenient application for elderly people or those who are unable to rinse/gargle.
新冠病毒的最高病毒载量可在口腔中检测到，因此通过鼻腔和口腔喷雾减少传染性病毒的方法可能会降低传播风险。因此，根据 EN 14476，评估了九种鼻腔和口腔喷雾的灭活能力。一种基于次氯酸钠的鼻腔喷雾和一种含有精油的口腔喷雾将病毒滴度降低了两到三个数量级。尽管临床数据仍然很少，但鼻腔和口腔喷雾为老年人或无法漱口/漱口的人提供了更方便的应用。
