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具有不寻常组织学特征的新发组织样麻风

De Novo Histoid Leprosy With Unusual Histological Features.

作者信息

Samiey Fatima, Aljalahma Jawaher, Al Awadhi Ameen

机构信息

Dermatology, Salmaniya Medical Complex, Manama, BHR.

出版信息

Cureus. 2021 Nov 3;13(11):e19230. doi: 10.7759/cureus.19230. eCollection 2021 Nov.

DOI:10.7759/cureus.19230
PMID:34754702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8569650/
Abstract

Histoid leprosy is a type of multibacillary leprosy that has unique clinical and histological characteristics. Some consider it to be an entity of its own, whereas others view it as a variant of lepromatous leprosy. Histoid leprosy can either occur 'de-novo', or secondarily in patients who relapse after dapsone monotherapy or in the presence of dapsone resistance. Here is a case that presented with clinical features of histoid leprosy but also with classic histologic features of lepromatous leprosy, deeming it very distinctive and unusual.

摘要

组织样麻风是一种多菌型麻风,具有独特的临床和组织学特征。一些人认为它是一种独立的疾病实体,而另一些人则将其视为瘤型麻风的一种变体。组织样麻风既可以“原发性”发生,也可继发于接受氨苯砜单药治疗后复发或存在氨苯砜耐药的患者。本文报告一例具有组织样麻风临床特征,但同时具有瘤型麻风典型组织学特征的病例,该病例非常独特且罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/9e0adbbe2dbd/cureus-0013-00000019230-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/9b2fc1c421a1/cureus-0013-00000019230-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/f09405461ca1/cureus-0013-00000019230-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/ad379c08482b/cureus-0013-00000019230-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/9e0adbbe2dbd/cureus-0013-00000019230-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/9b2fc1c421a1/cureus-0013-00000019230-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/f09405461ca1/cureus-0013-00000019230-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/ad379c08482b/cureus-0013-00000019230-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0b9/8569650/9e0adbbe2dbd/cureus-0013-00000019230-i04.jpg

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De Novo Histoid Leprosy With Unusual Histological Features.具有不寻常组织学特征的新发组织样麻风
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引用本文的文献

1
Leprosy Classification, Clinical Features, Epidemiology, and Host Immunological Responses: Failure of Eradication in 2023.麻风病的分类、临床特征、流行病学及宿主免疫反应:2023年根除失败情况
Cureus. 2023 Sep 6;15(9):e44767. doi: 10.7759/cureus.44767. eCollection 2023 Sep.

本文引用的文献

1
Histoid leprosy presenting with figurate lesions: A unique and rare presentation.以多形性皮损为表现的组织样麻风:一种独特且罕见的表现形式。
Indian J Dermatol Venereol Leprol. 2018 Nov-Dec;84(6):736-739. doi: 10.4103/ijdvl.IJDVL_475_17.
2
De-novo histoid leprosy.新发组织样麻风
J Lab Physicians. 2011 Jul;3(2):110-2. doi: 10.4103/0974-2727.86844.
3
Histoid leprosy: histopathological connotations' relevance in contemporary context.组织样麻风:组织病理学内涵在当代背景下的相关性
Am J Dermatopathol. 2009 May;31(3):268-71. doi: 10.1097/DAD.0b013e318185d1d0.