Holford Sam, Viner William, Hunt James
Department of Obstetrics & Gynaecology, Taranaki District Health Board, Private Bag 2016, New Plymouth 4342, New Zealand.
Taranaki Pathology Services, PO Box 3300, Fitzroy, New Plymouth 4312, New Zealand.
Case Rep Womens Health. 2021 Oct 21;32:e00366. doi: 10.1016/j.crwh.2021.e00366. eCollection 2021 Oct.
This is the first report of well-differentiated papillary mesothelioma (WDPM) found concurrently with struma ovarii. These rare tumors have no know association, and are considered benign, though malignant transformation of WDPM has been described. After treatment of WDPM, follow-up surveillance has been suggested in the literature, though a method has not been described and an evidence base is lacking. Pre-operative imaging by computed tomography and ultrasound did not identify the WDPM, calling into question the role of imaging-based follow-up. Furthermore, malignant transformation has been reported only outside of the typical 5-year follow-up window. The authors of this case report suggest rationalization of follow-up of WDPM, acknowledging the risks and unknown harms of scheduled imaging follow-up.
这是首例关于同时发现高分化乳头状间皮瘤（WDPM）与卵巢甲状腺肿的报告。这些罕见肿瘤之间尚无已知关联，虽有WDPM发生恶性转化的描述，但它们被认为是良性的。WDPM治疗后，文献中建议进行随访监测，不过尚未描述具体方法且缺乏循证依据。术前计算机断层扫描和超声成像未发现WDPM，这使基于成像的随访作用受到质疑。此外，恶性转化仅在典型的5年随访期之外有报道。本病例报告的作者建议对WDPM随访进行合理化，同时承认定期成像随访存在的风险和未知危害。
