Department of Dermatology, Singapore General Hospital.
Dermatol Online J. 2021 Sep 15;27(9). doi: 10.5070/D327955144.
Cutaneous sarcoidosis has a wide variety of manifestations and can be challenging to diagnose clinically. Dermoscopy is a useful tool to support the clinical diagnosis. Herein, we report an elderly woman with pruritic facial plaques. Dermoscopy showed translucent orange globules with shiny white lines, and microscopic examination showed non-necrotizing granulomas with perigranulomatous fibrosis. Shiny white structures on dermoscopy are conventionally associated with basal cell carcinoma, melanoma, and dermatofibroma, and have not yet been reported in sarcoidosis. Current descriptions of dermoscopy findings of sarcoidosis in the literature are summarized. Further differential diagnostic entities for this presentation are described and treatment options for cutaneous sarcoidosis are discussed.
皮肤结节病表现多样，临床诊断具有挑战性。皮肤镜检查是支持临床诊断的有用工具。本文报道了一例老年女性面部瘙痒斑块患者。皮肤镜下可见半透明橙黄色小球，伴有闪亮的白色线条，显微镜检查显示非坏死性肉芽肿伴围肉芽肿纤维化。皮肤镜下闪亮的白色结构通常与基底细胞癌、黑色素瘤和皮肤纤维瘤相关，尚未在结节病中报道。本文总结了目前文献中对结节病皮肤镜检查结果的描述。进一步描述了该表现的其他鉴别诊断实体，并讨论了皮肤结节病的治疗选择。
