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使用反射式共聚焦显微镜对一例皮肤结节病进行体内评估。

In-vivo assessment of a case of cutaneous sarcoidosis using reflectance confocal microscopy.

作者信息

Pasquali Paola, Gonzalez Salvador, Fortuño Angeles, Freites-Martinez Azael

机构信息

Dermatology Department, Pius Hospital de Valls, Tarragona, Spain.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, United States Of America.

出版信息

An Bras Dermatol. 2019 Jan-Feb;94(1):93-95. doi: 10.1590/abd1806-4841.20197315.

DOI:10.1590/abd1806-4841.20197315
PMID:30726472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6360958/
Abstract

Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that allows visualization of the epidermis and papillary dermis with cellular-level resolution. Granulomatous reactions such as sarcoidosis could be assessed using RCM. The identification of bright beaded-like structures that could correspond to reticulin fibers overlying granulomas, in association with dermoscopy, may be a very useful approach in the diagnosis of sarcoidosis and for the differentiation of this granulomatous entity with superficial cutaneous metastasis.

摘要

反射式共聚焦显微镜(RCM)是一种非侵入性成像技术,可在细胞水平分辨率下实现对表皮和乳头层真皮的可视化。诸如结节病等肉芽肿反应可通过RCM进行评估。结合皮肤镜检查,识别可能对应于肉芽肿上方网状纤维的明亮串珠状结构,可能是诊断结节病以及鉴别这种肉芽肿性病变与浅表皮肤转移瘤的非常有用的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/0b49a5e2e461/abd-94-01-0093-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/87b55d2a62f3/abd-94-01-0093-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/0092c711f79f/abd-94-01-0093-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/1453f5bcdedb/abd-94-01-0093-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/0b49a5e2e461/abd-94-01-0093-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/87b55d2a62f3/abd-94-01-0093-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/0092c711f79f/abd-94-01-0093-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/1453f5bcdedb/abd-94-01-0093-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf4/6360958/0b49a5e2e461/abd-94-01-0093-g04.jpg

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本文引用的文献

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Acquired anhidrosis associated with systemic sarcoidosis: quantification of nerve fibres around eccrine glands by confocal microscopy.与系统性结节病相关的获得性无汗症:通过共聚焦显微镜对小汗腺周围神经纤维进行定量分析
Br J Dermatol. 2018 Jan;178(1):e59-e61. doi: 10.1111/bjd.15880. Epub 2017 Dec 14.
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Is confocal microscopy a valuable tool in diagnosing nodular lesions? A study of 140 cases.共聚焦显微镜在诊断结节性病变中的价值?140 例研究。
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Dermoscopy of cutaneous sarcoidosis.皮肤结节病的皮肤镜检查。
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成人口周皮炎的反射式共聚焦显微镜检查:一例报告
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