Liu Yu Chia, Tseng Huai-Hsuan, Chang Yun-Hsuan, Chang Hui Hua, Yang Yen Kuang, Chen Po See
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Psychiatry, Tainan Municipal Hospital (managed by Show Chwan Medical Care Corporation), Tainan, Taiwan.
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
J Formos Med Assoc. 2020 Oct 23. doi: 10.1016/j.jfma.2020.10.012.
BACKGROUND/PURPOSE: Although social cognitive deficits were found in euthymic patients of bipolar disorder (BD), the characteristics of social cognition in Han Chinese euthymic BD patients remain obscure. This study aimed to examine social cognition in Han Chinese euthymic BD patients relative to healthy controls (HC). Moreover, we explore the differences in social cognition between euthymic BD I and BD II patients.
43 Han Chinese BD patients (BD-I:25, BD-II:18) and 28 HC were recruited. All patients were euthymic (Young Mania Rating Scale (YMRS) ≤ 7 and Hamilton Depression Rating Scale (HDRS) ≤ 7). Social cognitive ability was measured using Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT), including 4 branches: perceiving emotions, facilitating emotions, understanding emotions, and managing emotions. Continuous performance Test (CPT) and Wisconsin Card Sorting Test (WCST) were used to examine attention and executive function.
Significant difference in understanding emotions branch of MSCEIT was found between BD patients and HCs (Mann-Whitney U test, p = 0.005). Besides, BD patients had significantly worse performance in WCST and CPT. However, the differences in WCST, CPT, MSCEIT total scores and its subscales were not significant between BD I and BD II patients.
Euthymic Han Chinese BD patients exhibit significant social cognitive deficits in understanding emotion and cognitive dysfunction in attention and executive function. Furthermore, Han Chinese BD I patients showed similar social cognitive and general cognitive ability as compared with BD II patients. Social cognitive rehabilitation on both euthymic BD I and II patients should be considered.
背景/目的：尽管在双相情感障碍（BD）的心境正常患者中发现了社会认知缺陷，但汉族心境正常的BD患者的社会认知特征仍不清楚。本研究旨在探讨汉族心境正常的BD患者与健康对照者（HC）相比的社会认知情况。此外，我们还探讨了心境正常的BD-I型和BD-II型患者在社会认知方面的差异。
招募了43名汉族BD患者（BD-I型：25名，BD-II型：18名）和28名HC。所有患者均为心境正常（杨氏躁狂量表（YMRS）≤7且汉密尔顿抑郁量表（HDRS）≤7）。使用梅耶-萨洛维-卡鲁索情商测试（MSCEIT）测量社会认知能力，包括4个分支：感知情绪、促进情绪、理解情绪和管理情绪。采用连续性能测试（CPT）和威斯康星卡片分类测试（WCST）来检查注意力和执行功能。
BD患者与HC在MSCEIT的理解情绪分支上存在显著差异（曼-惠特尼U检验，p = 0.005）。此外，BD患者在WCST和CPT中的表现明显更差。然而，BD-I型和BD-II型患者在WCST、CPT、MSCEIT总分及其子量表上的差异并不显著。
心境正常的汉族BD患者在理解情绪方面表现出显著的社会认知缺陷，在注意力和执行功能方面存在认知功能障碍。此外，与BD-II型患者相比，汉族BD-I型患者表现出相似的社会认知和一般认知能力。应考虑对心境正常的BD-I型和II型患者进行社会认知康复。
