1Companion Animal Euthanasia Training Academy, Loveland, CO.
25280 Veterinary Care, Denver, CO.
Am J Vet Res. 2021 Nov 10;83(1):95-99. doi: 10.2460/ajvr.21.08.0123.
To determine whether intrarenal injection of sodium pentobarbital is a viable method for euthanasia in anesthetized client-owned cats and assess potential factors associated with time to cardiopulmonary arrest (TCPA) for such treated cats.
131 client-owned cats.
In this retrospective study, client-owned cats presented for euthanasia between March 1, 2009, and January 15, 2010, were evaluated by veterinarians to determine suitability of intrarenal injection versus other methods of euthanasia. Cats included were anesthetized and then received 6 mL of sodium pentobarbital (390 mg/mL) by intrarenal injection. Results for TCPA were compared for cats grouped on the basis of variables of interest.
131 cats were included, of which 74 (79%) had a TCPA < 1 minute and 28 (21%) had a TCPA between 1.5 and 8 minutes after intrarenal injection. Most (124/131 [95%]) cats had no observable reaction to the intrarenal injection other than cardiopulmonary arrest. Median TCPA was longer for cats without (1 min; 25/131 [19%]) versus with (0 min; 106/131 [81%]) palpable kidney swelling upon injection.
The effects of intrarenal injection of sodium pentobarbital in cats of the present study were similar to those typically observed with IV administration of euthanasia solution. When this intrarenal injection method is used, cardiopulmonary arrest with few agonal reactions can be expected to occur quickly in most patients. The intrarenal injection method is suited for euthanasia of anesthetized cats with easily located kidneys when IV access may be difficult.
确定经肾内注射戊巴比妥钠是否为麻醉状态下患宠猫安乐死的可行方法,并评估此类治疗猫发生心肺停止(TCPA)的潜在相关因素。
131 只患宠猫。
在这项回顾性研究中,兽医评估了 2009 年 3 月 1 日至 2010 年 1 月 15 日期间因安乐死而就诊的患宠猫,以确定经肾内注射与其他安乐死方法相比是否合适。麻醉后的猫经肾内注射 6 mL 戊巴比妥钠(390 mg/mL)。根据感兴趣的变量对 TCPA 结果进行分组比较。
共纳入 131 只猫,其中 74 只(79%)在经肾内注射后 1 分钟内发生 TCPA,28 只(21%)在 1.5 至 8 分钟内发生 TCPA。除心肺停止外,大多数(131 只中的 124 只[95%])猫对经肾内注射没有其他可观察到的反应。与注射后无(1 分钟;25 只[19%])可触及肾肿胀的猫相比,无(0 分钟;106 只[81%])可触及肾肿胀的猫 TCPA 中位数更长。
本研究中猫经肾内注射戊巴比妥钠的效果与通常观察到的 IV 给予安乐死溶液的效果相似。当使用这种经肾内注射方法时,大多数患者可迅速发生无濒死反应的心肺停止。当 IV 通路可能难以建立时,该经肾内注射方法适用于麻醉状态下且肾脏易于定位的猫的安乐死。