Department of Psychiatry, Enam Medical College and Hospital, Dhaka, Bangladesh.
Pi Research Consultancy Center, Dhaka, Bangladesh.
Brain Behav. 2021 Dec;11(12):e2409. doi: 10.1002/brb3.2409. Epub 2021 Nov 10.
Our knowledge of suicide in low-income countries is limited. Understanding the importance of factors that contribute to suicide risk will allow for the appropriate allocation of limited resources. In order to prioritize suicide prevention activities in Bangladesh, we estimate the fractions of suicides attributable to key risk factors.
Using data from matched cases (100) and controls (100) as part of a psychological autopsy study in Dhaka, we estimate the population attributable fraction for key clinical (psychiatric disorders and physical disability), and social (life events, psychical and/or sexual abuse, unemployment, and social isolation) risk factors for suicide in Bangladesh.
Assuming a causal relationship, life events were responsible for the largest proportion of suicide deaths (85.9%; confidence interval [CI], 79.6-90.2), followed by mental disorder (49.5%; CI, 45.3-53.4). The population attributable fraction for the risk factors was 42.9% (CI, 40.6-45) for depression, 11% (CI, 8.9-13) for sexual abuse, and 34.9% (CI, 10.1-52.9) for social isolation.
The study determined the population attributable fraction of risk factors for suicide in Bangladesh. Prevention strategies should be prioritized on the management of the aftermaths of adverse life events, treatment of psychiatric disorders, sexual abuse, and social isolation in the country.
我们对低收入国家自杀情况的了解有限。了解导致自杀风险的因素的重要性,将有助于合理分配有限的资源。为了在孟加拉国优先开展预防自杀活动,我们估算了导致自杀的关键风险因素的分数。
利用作为心理尸检研究的一部分的达卡匹配病例(100 例)和对照(100 例)的数据,我们估算了导致孟加拉国自杀的关键临床(精神障碍和身体残疾)和社会(生活事件、心理和/或性虐待、失业和社会孤立)风险因素的人群归因分数。
假设存在因果关系,生活事件导致自杀死亡的比例最大(85.9%;置信区间[CI],79.6-90.2),其次是精神障碍(49.5%;CI,45.3-53.4)。风险因素的人群归因分数为抑郁症 42.9%(CI,40.6-45),性虐待 11%(CI,8.9-13),社会孤立 34.9%(CI,10.1-52.9)。
本研究确定了导致孟加拉国自杀的风险因素的人群归因分数。预防策略应优先考虑管理不良生活事件的后果、治疗精神障碍、性虐待和社会孤立。