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血型与主动脉夹层的关系。

The Relationship between Blood Groups and Aortic Dissection.

出版信息

Clin Lab. 2021 Nov 1;67(11). doi: 10.7754/Clin.Lab.2021.210220.

DOI:10.7754/Clin.Lab.2021.210220
PMID:34758236
Abstract

BACKGROUND

Plenty of diseases have been found having associations with blood types, especially cardiovascular diseases. The purpose of this study was to clarify whether there is a relationship between blood groups and acute aortic dissection. We also further studied the distribution of blood groups in different types of acute aortic dissection.

METHODS

A total of 291 patients diagnosed with acute aortic dissection from 2011 to 2018 were enrolled and analyzed retrospectively in this study. The control group consisted of 582 patients who received plastic surgery at West China hospital from 2011 to 2018. First, we analyzed the distribution of blood groups between the study group and the control group, including the ABO, Rh, O and non-O groups. Then, we further divided the study group into two groups by the type of acute aortic dissection to determine if there was difference in blood groups between the two types of acute aortic dissection.

RESULTS

The analysis of the distribution of ABO blood groups (p = 0.302) and Rh blood groups (p = 0.502) did not reveal statistically significant differences. There were no statistically significant differences in the distributions of ABO blood groups and Rh blood groups in different types of acute aortic dissection.

CONCLUSIONS

Our study did not prove the incidence of acute aortic dissection, or the type of acute aortic dissection had a relationship with common blood groups.

摘要

背景

大量疾病已被发现与血型有关,尤其是心血管疾病。本研究旨在阐明血型与急性主动脉夹层之间是否存在关系。我们还进一步研究了不同类型急性主动脉夹层中血型的分布。

方法

本研究回顾性分析了 2011 年至 2018 年间我院收治的 291 例急性主动脉夹层患者。对照组为同期在我院接受整形手术的 582 例患者。首先,我们分析了研究组和对照组之间的血型分布,包括 ABO、Rh、O 型和非 O 型。然后,我们根据急性主动脉夹层的类型进一步将研究组分为两组,以确定两种类型的急性主动脉夹层之间的血型是否存在差异。

结果

ABO 血型(p = 0.302)和 Rh 血型(p = 0.502)的分布分析差异无统计学意义。不同类型急性主动脉夹层中 ABO 血型和 Rh 血型的分布差异无统计学意义。

结论

本研究未能证明急性主动脉夹层的发生率或不同类型急性主动脉夹层与常见血型之间存在关系。

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