Department of Cardiology, Toyohashi Heart Center, Aichi, Japan.
J Endovasc Ther. 2022 Aug;29(4):536-543. doi: 10.1177/15266028211057091. Epub 2021 Nov 10.
The endovascular approach for eccentric calcified lesions of the no-stenting zone is challenging. This study aimed to investigate the effect of a novel technique for these lesions.
We performed EVT for severe and eccentric calcified lesions using the technique, which is presented previously and named aggressive wire recanalization in calcified atheroma and dilatation (ARCADIA). In brief, a guidewire is passed to the residual lumen firstly. Next, another guidewire is advanced into and cross through the calcified plaque and returned to the distal original lumen with intravascular ultrasound (IVUS) guided. The calcified plaque is dilated by using a scoring-balloon or non-compliant balloon.
Consecutive 14 peripheral artery disease patients with isolated and eccentric calcification in a no-stenting zone were treated using ARCADIA technique between January 2018 and March 2020. In IVUS data, lumen cross-section area was significantly increased from 5.2 ± 2.0 mm to 18.1 ± 6.9 mm (p < 0.01), lumen area was expanded roundly evaluating as symmetry index from 0.45 ± 0.09 to 0.81 ± 0.12 (p < 0.01). There were no distal embolization and perforation after ARCADIA technique. One-year target lesion revascularization occurred in only 2 cases. The primary patency of 1 year was 85.7%.
ARCADIA technique is safe and appropriate, and can be 1 option to treat for eccentric calcified lesions of the no-stenting zone as an optimal wire crossing method.
血管内治疗(EVT)无支架区偏心钙化病变具有挑战性。本研究旨在探讨一种治疗此类病变的新技术的效果。
我们对严重且偏心钙化的病变采用一种新的技术进行 EVT,该技术先前已被报道并命名为积极导丝再通在钙化动脉粥样硬化和扩张(ARCADIA)。简要地说,首先将导丝穿过残留管腔。接下来,另一条导丝穿过钙化斑块并在血管内超声(IVUS)引导下返回远端原始管腔。用切割球囊或非顺应性球囊扩张钙化斑块。
2018 年 1 月至 2020 年 3 月,采用 ARCADIA 技术治疗了 14 例外周动脉疾病患者,这些患者均存在孤立性和无支架区偏心钙化。在 IVUS 数据中,管腔横截面积从 5.2±2.0mm 显著增加至 18.1±6.9mm(p<0.01),管腔面积均匀扩张,对称性指数从 0.45±0.09 增加至 0.81±0.12(p<0.01)。ARCADIA 技术后无远端栓塞和穿孔。仅 2 例发生 1 年时的靶病变血运重建。1 年的初始通畅率为 85.7%。
ARCADIA 技术安全且适用,作为一种最佳的导丝通过方法,是治疗无支架区偏心钙化病变的一种选择。