Piórek Aleksandra, Tabor Sylwia, Jaśkiewicz Piotr, Kasprowicz Anetta, Zaborowska-Szmit Magdalena, Winiarczyk Kinga, Płużański Adam, Kowalski Dariusz, Krzakowski Maciej
Lung Cancer and Chest Tumors Department, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Brachytherapy Department, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
J Contemp Brachytherapy. 2021 Oct;13(5):588-592. doi: 10.5114/jcb.2021.109853. Epub 2021 Oct 8.
Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment.
The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence.
Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control.
气管腺样囊性癌（ACC）是一种相对罕见的恶性肿瘤，目前缺乏关于其治疗效果的前瞻性临床试验。大多数作者倾向于手术切除，若切除不完全则术后进行放射治疗。目前尚无关于复发后治疗的前瞻性数据。
本文介绍了一名年轻女性气管ACC病例，由于术后出现神经并发症，需要进一步诊断、管理和治疗，因此仅接受了手术切除，未进行放射治疗。气管手术后脊髓功能障碍作为一种并发症本身极为罕见，该患者疾病复发后成功接受了根治性放疗和近距离放疗。
神经并发症导致术后未进行放射治疗可能是该患者ACC复发的原因。复发性疾病切除不完全后进行放射治疗可能会实现长期的局部控制。
