视神经脊髓炎谱系障碍患者的颅内压升高
Increased Intracranial Pressure on a Patient with Neuromyelitis Optica Spectrum Disorder.
作者信息
Forouzannia Seyed Mohammad, Yarahmadi Pourya, Alirezaei Mohammad, Rezaeimanesh Nasim, Naser Moghadasi Abdorreza
机构信息
Multiple Sclerosis Research Center; Neuroscience institute; Tehran University of Medical Sciences; Tehran; Iran.
出版信息
Caspian J Intern Med. 2021;12(Suppl 2):S435-S438. doi: 10.22088/cjim.12.0.435.
BACKGROUND
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathic disease affecting central nervous system (CNS). CSF pressure in these patients is usually normal.
CASE PRESENTATION
A 30-year-old woman was admitted with complaints of headache and lower limbs paresis. Lumbar puncture (LP) and magnetic resonance imaging were performed for the patient. Opening pressure was 42 cm H2O in the first LP. According to the clinical evidences, imaging, and the patient's positive aquaporin-4 antibody, the diagnosis of NMOSD was established.
CONCLUSION
High intracranial pressure headache; however rare, may be the first sign of the onset of the acute exacerbation phase of NMOSD.
背景
视神经脊髓炎谱系障碍（NMOSD）是一种影响中枢神经系统（CNS）的自身免疫性星形细胞病。这些患者的脑脊液压力通常正常。
病例报告
一名30岁女性因头痛和下肢无力入院。对该患者进行了腰椎穿刺（LP）和磁共振成像检查。首次腰椎穿刺时的初压为42 cm H₂O。根据临床证据、影像学检查以及患者水通道蛋白4抗体阳性，确诊为NMOSD。
结论
高颅内压性头痛；然而罕见，可能是NMOSD急性加重期发作的首发症状。
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