Huang Bin, Mao Lijun, Shi Xueliang, Yang Hai-Bo
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University 3663 N. Zhongshan Road Shanghai 200062 P. R. China
Chem Sci. 2021 Sep 2;12(41):13648-13663. doi: 10.1039/d1sc01618k. eCollection 2021 Oct 27.
Supramolecular radical chemistry has been emerging as a cutting-edge interdisciplinary field of traditional supramolecular chemistry and radical chemistry in recent years. The purpose of such a fundamental research field is to combine traditional supramolecular chemistry and radical chemistry together, and take the benefit of both to eventually create new molecules and materials. Recently, supramolecular radical cages have been becoming one of the most frontier and challenging research focuses in the field of supramolecular chemistry. In this , we give a brief introduction to organic radical chemistry, supramolecular chemistry, and the emerging supramolecular radical chemistry along with their history and application. Subsequently, we turn to the main part of this topic: supramolecular radical cages. The design and synthesis of supramolecular cages consisting of redox-active building blocks and radical centres are summarized. The host-guest interactions between supramolecular (radical) cages and organic radicals are also surveyed. Some interesting properties and applications of supramolecular radical cages such as their unique spin-spin interactions and intriguing confinement effects in radical-mediated/catalyzed reactions are comprehensively discussed and highlighted in the main text. The purpose of this is to help students and researchers understand the development of supramolecular radical cages, and potentially to stimulate innovation and creativity and infuse new energy into the fields of traditional supramolecular chemistry and radical chemistry as well as supramolecular radical chemistry.
近年来，超分子自由基化学已成为传统超分子化学和自由基化学的一个前沿交叉领域。这一基础研究领域的目的是将传统超分子化学和自由基化学结合起来，兼收二者之长，最终创造新的分子和材料。最近，超分子自由基笼已成为超分子化学领域最前沿且最具挑战性的研究热点之一。在此，我们简要介绍有机自由基化学、超分子化学以及新兴的超分子自由基化学及其历史和应用。随后，我们进入本主题的主要部分：超分子自由基笼。总结了由氧化还原活性构建块和自由基中心组成的超分子笼的设计与合成。还考察了超分子（自由基）笼与有机自由基之间的主客体相互作用。超分子自由基笼的一些有趣性质和应用，如它们独特的自旋 - 自旋相互作用以及在自由基介导/催化反应中引人入胜的限域效应，将在正文部分进行全面讨论和重点突出。本文的目的是帮助学生和研究人员了解超分子自由基笼的发展，并有可能激发创新和创造力，为传统超分子化学、自由基化学以及超分子自由基化学领域注入新的活力。
