McDowell H P, Shears P, Hart C A, Martin J
Arch Dis Child. 1987 Jun;62(6):573-5. doi: 10.1136/adc.62.6.573.
A cross sectional study was carried out in children receiving treatment for acute lymphoblastic leukaemia to determine the prevalence of trimethoprim resistant organisms in their gut flora and to compare this with a control population. There was a significantly higher prevalence of trimethoprim resistant bacteria in the study group (61%) compared with controls (14%). A longitudinal study showed that emergence of these organisms was intermittent during treatment.
一项横断面研究在接受急性淋巴细胞白血病治疗的儿童中开展,以确定其肠道菌群中对甲氧苄啶耐药的微生物的流行情况,并与对照组人群进行比较。与对照组(14%)相比,研究组中对甲氧苄啶耐药细菌的流行率显著更高(61%)。一项纵向研究表明,这些微生物在治疗期间的出现是间歇性的。