• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Acute lymphoblastic leukaemia: trimethoprim resistant organisms during treatment.急性淋巴细胞白血病：治疗期间对甲氧苄啶耐药的微生物。
Arch Dis Child. 1987 Jun;62(6):573-5. doi: 10.1136/adc.62.6.573.
2
The effect of trimethoprim-sulphonamide, trimethoprim and sulphonamide on the occurrence of resistant enterobacteriaceae in human intestinal flora.
Infection. 1979;7 Suppl 4:S321-3. doi: 10.1007/BF01639007.
3
Effect of trimethoprim on the occurrence of drug-resistant coliform bacteria in the faecal flora.甲氧苄啶对粪便菌群中耐药性大肠菌发生情况的影响。
Chemotherapy. 1976;22(2):97-103. doi: 10.1159/000221918.
4
Trimethoprim resistance plasmids.甲氧苄啶耐药质粒
Ann Microbiol (Paris). 1984 Sep-Oct;135B(2):177-86.
5
Trimethoprim-resistant Enterobacteriaceae in urinary tract infection.尿路感染中对甲氧苄啶耐药的肠杆菌科细菌
Can Med Assoc J. 1975 Jun 14;112(13 Spec No):54-8.
6
Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children.长期服用甲氧苄啶/磺胺甲恶唑对儿童肠道菌群耐药性及整合子流行率的影响：一项随机、双盲、安慰剂对照试验
J Antimicrob Chemother. 2009 May;63(5):1011-6. doi: 10.1093/jac/dkp050. Epub 2009 Mar 18.
7
Failure of oral trimethoprim-sulfamethoxazole prophylaxis in acute leukemia: isolation of resistant plasmids from strains of Enterobacteriaceae causing bacteremia.急性白血病患者口服甲氧苄啶-磺胺甲恶唑预防用药失败：从引起菌血症的肠杆菌科菌株中分离出耐药质粒。
N Engl J Med. 1982 Jan 7;306(1):16-20. doi: 10.1056/NEJM198201073060105.
8
Long-term low-dose co-trimoxazole in prophylaxis of childhood urinary tract infection: bacteriological aspects.长期小剂量复方新诺明预防儿童尿路感染：细菌学方面
Br Med J. 1976 Jul 24;2(6029):206-8. doi: 10.1136/bmj.2.6029.206.
9
Trimethoprim--resistant coliforms.耐甲氧苄啶大肠菌群
Lancet. 1977 Oct 29;2(8044):926.
10
Multivariate study of enterobacteria and Pseudomonas in saliva of patients with acute leukemia.急性白血病患者唾液中肠杆菌和假单胞菌的多变量研究
Oral Surg Oral Med Oral Pathol. 1991 Sep;72(3):300-8. doi: 10.1016/0030-4220(91)90219-3.

引用本文的文献

1
Occurrence of multiple antibiotic resistance and R plasmids in Enterobacteriaceae isolated from children in the Sudan.苏丹儿童分离出的肠杆菌科细菌中多重耐药性和R质粒的出现情况。
Epidemiol Infect. 1988 Feb;100(1):73-81. doi: 10.1017/s0950268800065572.

本文引用的文献

1
Resistance among fecal flora of patients taking sulfamethoxazole-trimethoprim or trimethoprim alone.服用复方磺胺甲恶唑或单独服用甲氧苄啶患者粪便菌群的耐药性。
Antimicrob Agents Chemother. 1981 Jan;19(1):33-8. doi: 10.1128/AAC.19.1.33.
2
Emergence of high-level trimethoprim resistance in fecal Escherichia coli during oral administration of trimethoprim or trimethoprim--sulfamethoxazole.口服甲氧苄啶或甲氧苄啶-磺胺甲恶唑期间粪便中大肠杆菌出现高水平甲氧苄啶耐药性。
N Engl J Med. 1982 Jan 21;306(3):130-5. doi: 10.1056/NEJM198201213060302.
3
Enteropathy complicating maintenance therapy in acute lymphoblastic leukaemia.急性淋巴细胞白血病维持治疗中并发的肠病
Arch Dis Child. 1982 Sep;57(9):663-7. doi: 10.1136/adc.57.9.663.
4
Trimethoprim/sulfamethoxazole prophylaxis in neutropenic patients. Reduction of infections and effect on bacterial and fungal flora.
Am J Med. 1983 Apr;74(4):599-607. doi: 10.1016/0002-9343(83)91017-3.
5
Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia.三甲氧苄氨嘧啶-磺胺甲基异噁唑联合两性霉素B预防急性非淋巴细胞白血病患者感染
Ann Intern Med. 1981 Nov;95(5):555-9. doi: 10.7326/0003-4819-95-5-555.
6
Nosocomial gentamicin- and multiply-resistant enterobacteria at one hospital. Factors associated with carriage.
J Hosp Infect. 1982 Jun;3(2):165-72. doi: 10.1016/0195-6701(82)90009-3.
7
Co-trimoxazole alone for prevention of bacterial infection in patients with acute leukaemia.单独使用复方新诺明预防急性白血病患者的细菌感染。
Lancet. 1982 Jan 2;1(8262):5-6. doi: 10.1016/s0140-6736(82)92553-3.
8
Use of trimethoprim-sulfamethoxazole to prevent bacterial infections in children with acute lymphoblastic leukemia.使用甲氧苄啶-磺胺甲恶唑预防急性淋巴细胞白血病患儿的细菌感染。
Pediatr Infect Dis. 1985 May-Jun;4(3):265-9. doi: 10.1097/00006454-198505000-00012.
9
Transposition of a deoxyribonucleic acid sequence encoding trimethoprim and streptomycin resistances from R483 to other replicons.编码甲氧苄啶和链霉素抗性的脱氧核糖核酸序列从R483转位至其他复制子。
J Bacteriol. 1976 Mar;125(3):800-10. doi: 10.1128/jb.125.3.800-810.1976.
10
Successful chemoprophylaxis for Pneumocystis carinii pneumonitis.卡氏肺孢子虫肺炎的成功化学预防。
N Engl J Med. 1977 Dec 29;297(26):1419-26. doi: 10.1056/NEJM197712292972602.

急性淋巴细胞白血病：治疗期间对甲氧苄啶耐药的微生物。

Acute lymphoblastic leukaemia: trimethoprim resistant organisms during treatment.

作者信息

McDowell H P, Shears P, Hart C A, Martin J

出版信息

Arch Dis Child. 1987 Jun;62(6):573-5. doi: 10.1136/adc.62.6.573.

DOI:10.1136/adc.62.6.573
PMID:3476023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1778445/
Abstract

A cross sectional study was carried out in children receiving treatment for acute lymphoblastic leukaemia to determine the prevalence of trimethoprim resistant organisms in their gut flora and to compare this with a control population. There was a significantly higher prevalence of trimethoprim resistant bacteria in the study group (61%) compared with controls (14%). A longitudinal study showed that emergence of these organisms was intermittent during treatment.

摘要

一项横断面研究在接受急性淋巴细胞白血病治疗的儿童中开展，以确定其肠道菌群中对甲氧苄啶耐药的微生物的流行情况，并与对照组人群进行比较。与对照组（14%）相比，研究组中对甲氧苄啶耐药细菌的流行率显著更高（61%）。一项纵向研究表明，这些微生物在治疗期间的出现是间歇性的。