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HELLP综合征:一例通过剪切波弹性成像、剪切波频散及衰减成像相关性显示肝脏实质回声发生区域性改变的超声病例。

HELLP syndrome: An ultrasound case of geographically altered liver parenchymal echogenicity with shear wave elastography, shear wave dispersion and attenuation imaging correlation.

作者信息

Mould Andrea, Abbott Steven, Welman Christopher J

机构信息

Department of Medical Imaging Fiona Stanley Hospital Murdoch WA 6150 Australia.

出版信息

Australas J Ultrasound Med. 2019 Nov 5;23(2):149-155. doi: 10.1002/ajum.12185. eCollection 2020 May.

DOI:10.1002/ajum.12185
PMID:34760595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8411737/
Abstract

HELLP syndrome is a rare, potentially life threatening obstetric condition that is diagnosed by the combination of Haemolysis, Elevated Liver enzyme levels, and Low Platelets (, 1, 164, 2011). HELLP affects between 0.5% and 0.9% of all pregnancies (, 9, 8, 2009), however less than 0.5% of HELLP syndrome cases demonstrate any imaging abnormalities ( 185, 1205, 2005). This case report outlines the use of three new liver ultrasound technologies - shear wave elastography (SWE), shear wave dispersion (SWD) and attenuation imaging (ATI) in the evaluation of a patient with HELLP syndrome. The ultrasound applications were used to examine temporal changes of the disease with corresponding biochemical variations. The SWE and SWD values correlated with B mode ultrasound imaging and the clinical findings of HELLP.

摘要

HELLP综合征是一种罕见的、可能危及生命的产科疾病,通过溶血、肝酶水平升高和血小板减少三联征进行诊断(,1, 164, 2011)。HELLP影响所有妊娠的0.5%至0.9%(,9, 8, 2009),然而,不到0.5%的HELLP综合征病例显示有任何影像学异常(185, 1205, 2005)。本病例报告概述了三种新的肝脏超声技术——剪切波弹性成像(SWE)、剪切波频散(SWD)和衰减成像(ATI)在评估一名HELLP综合征患者中的应用。这些超声应用用于检查疾病的时间变化及相应的生化变化。SWE和SWD值与B型超声成像及HELLP的临床发现相关。

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Ultraschall Med. 2017 Aug;38(4):e16-e47. doi: 10.1055/s-0043-103952. Epub 2017 Apr 13.
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4
Shear wave elastography for evaluation of liver fibrosis.剪切波弹性成像技术用于评估肝纤维化。
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The HELLP syndrome: clinical issues and management. A Review.HELLP综合征:临床问题与管理。综述。
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Abdominal imaging features of HELLP syndrome: a 10-year retrospective review.
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Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count).
Am J Obstet Gynecol. 1992 Dec;167(6):1538-43. doi: 10.1016/0002-9378(92)91735-s.