Li Zongxue, Zhang Ze, Yu Jing, Du Xia, Lei Pinggui, Ruan Zhibing, Gao Bo
Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China.
ILIVER. 2023 Mar 4;2(1):56-66. doi: 10.1016/j.iliver.2023.02.003. eCollection 2023 Mar.
Pregnancy-related liver diseases are the most frequent cause of liver dysfunction in pregnancy and pose a real threat to fetal and maternal survival. Although hepatobiliary disorders are uncommon in pregnancy, they may be severe enough to cause risk to both the mother and fetus. There are five different types of liver disease that are unique to pregnancy, including hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, preeclampsia, hemolysis, elevated liver enzyme, and low platelet count syndrome, and acute fatty liver of pregnancy. Ultrasound, computed tomography, and magnetic resonance imaging play important roles in the rapid diagnosis and evaluation of complications. An accurate diagnosis can guide further treatment or the induction of labor to prevent intrauterine fetal death. This review highlights the pathogenesis, clinical features, imaging features, and treatment of pregnancy-related liver diseases with the aim of enhancing awareness of these rare but potentially life-threatening diseases of pregnancy.
妊娠相关肝病是孕期肝功能障碍最常见的原因,对胎儿和母亲的生存构成真正威胁。尽管肝胆疾病在孕期并不常见,但可能严重到对母亲和胎儿都造成风险。有五种不同类型的肝病是孕期特有的,包括妊娠剧吐、妊娠期肝内胆汁淤积症、子痫前期、溶血、肝酶升高和血小板减少综合征以及妊娠急性脂肪肝。超声、计算机断层扫描和磁共振成像在并发症的快速诊断和评估中发挥重要作用。准确的诊断可指导进一步治疗或引产,以防止宫内胎儿死亡。本综述重点介绍妊娠相关肝病的发病机制、临床特征、影像学特征和治疗方法,旨在提高对这些罕见但可能危及生命的妊娠疾病的认识。
ILIVER. 2023-3-4
Cochrane Database Syst Rev. 2017-1-15
1993
Evid Rep Technol Assess (Full Rep). 2009-3
Cochrane Database Syst Rev. 2017-11-28
Cochrane Database Syst Rev. 2022-5-13
Cochrane Database Syst Rev. 2016-5-22
Clin Med (Lond). 2021-9
Best Pract Res Clin Gastroenterol. 2020-2-18
Korean J Radiol. 2020-4
Expert Rev Gastroenterol Hepatol. 2020-1-20
Nat Rev Dis Primers. 2019-9-12
Semin Ultrasound CT MR. 2019-8
Curr Gastroenterol Rep. 2019-7-25