择期胃肠手术后中性粒细胞化学发光增强。
Enhancement of neutrophil chemiluminescence after elective gastrointestinal surgery.
作者信息
Waxman B P, Hastings M, Easmon C S, Dudley H A
出版信息
Aust N Z J Surg. 1987 Mar;57(3):185-9. doi: 10.1111/j.1445-2197.1987.tb01332.x.
Neutrophil count and luminol-dependent chemiluminescence were measured pre-operatively and on the second, sixth and ninth days after operation in nine patients undergoing major, elective gastrointestinal surgery. The aim of the study was to test the hypothesis that elective surgery as a form of injury has no prolonged deleterious effect on neutrophil activity in non-septic patients. A significant increase in neutrophil count was demonstrated in all patients at Day 2 (P less than 0.01) and Day 9 (P less than 0.01). Neutrophil chemiluminescence increased on Day 2 and Day 6, the increase on Day 6 being significant (P less than 0.02). In the first 9 days after elective gastrointestinal surgery, a biphasic neutrophilia occurs and the metabolic response of neutrophils to an opsonized particle is not impaired. These data would support the hypothesis that major elective surgery has no deleterious effects on neutrophil activity, and indeed that neutrophil activity may be enhanced.
对9名接受择期胃肠道大手术的患者在术前以及术后第2天、第6天和第9天进行了中性粒细胞计数和鲁米诺依赖的化学发光检测。本研究的目的是检验以下假设：作为一种损伤形式的择期手术对非脓毒症患者的中性粒细胞活性没有长期的有害影响。所有患者在术后第2天（P<0.01）和第9天（P<0.01）中性粒细胞计数显著增加。中性粒细胞化学发光在术后第2天和第6天增加，第6天的增加具有显著性（P<0.02）。在择期胃肠道手术后的前9天，出现双相中性粒细胞增多，并且中性粒细胞对调理素化颗粒的代谢反应未受损。这些数据支持以下假设：择期大手术对中性粒细胞活性没有有害影响，实际上中性粒细胞活性可能会增强。
Zotero 插件