鸟氨酸α-酮戊二酸（OAKG）治疗中风患者的对照试验。

Controlled trial of ornithine alpha ketoglutarate (OAKG) in patients with stroke.

作者信息

Woollard M L, Pearson R M, Dorf G, Griffith D, James I M

出版信息

Stroke. 1978 May-Jun;9(3):218-22. doi: 10.1161/01.str.9.3.218.

DOI:10.1161/01.str.9.3.218

Abstract

A double blind controlled trial of ornithine alpha-ketoglutarate (OAKG) was carried out on 50 patients admitted to the Royal Free and Royal Northern Hospitals, London, suffering from a recent stroke. Significant improvement was found in patients treated with OAKG when examined on the fifth day of therapy as compared to their control cases. The therapy was given for 5 days. When the patients in the treated and the control groups were compared 10 days after the beginning of treatment, there were no differences between the 2 groups. Implications of these findings are discussed.

摘要

对伦敦皇家自由医院和皇家北方医院收治的50例近期中风患者进行了鸟氨酸α-酮戊二酸（OAKG）双盲对照试验。与对照组相比，在治疗第5天检查时发现接受OAKG治疗的患者有显著改善。治疗持续5天。在治疗开始10天后比较治疗组和对照组患者时，两组之间没有差异。讨论了这些发现的意义。