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加拿大蒙特利尔儿童和青少年对 COVID-19 疫苗的接受和接种的社会不平等。

Social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents in Montreal, Canada.

机构信息

Centre for Public Health Research, University of Montreal, Pavillon 7101 avenue du Parc, Montreal, Quebec H3C 3J7, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario M5T 3M7, Canada.

Department of Microbiology, Infectious Diseases, and Immunology, University of Montreal, Pavillon Roger-Gaudry, 2900 boul. Édouard-Montpetit, Montréal, Québec H3T 1J4, Canada.

出版信息

Vaccine. 2021 Dec 3;39(49):7140-7145. doi: 10.1016/j.vaccine.2021.10.077. Epub 2021 Nov 8.

Abstract

BACKGROUND

The success of current and prospective COVID-19 vaccine campaigns for children and adolescents will in part depend on the willingness of parents to accept vaccination. This study examined social determinants of parental COVID-19 vaccine acceptance and uptake for children and adolescents.

METHODS

We used cross-sectional data from an ongoing COVID-19 cohort study in Montreal, Canada and included all parents of 2 to 18-year-olds who completed an online questionnaire between May 18 and June 26, 2021 (n = 809). We calculated child age-adjusted prevalence estimates of vaccine acceptance by parental education, race/ethnicity, birthplace, household income, and neighbourhood, and used multinomial logistic regression to estimate adjusted prevalence differences (aPD) and ratios (aPR). Social determinants of vaccine uptake were examined for the vaccine-eligible sample of 12 to 18 year-olds (n = 306).

RESULTS

Intention to vaccinate children against COVID-19 was high, with only 12.4% of parents unlikely to have their child vaccinated. Parents with younger children were less likely to accept vaccination, as were those from lower-income households, racialized groups, and those born outside Canada. Children from households with annual incomes <$100,000 had 18.4 percent lower prevalence of being vaccinated/very likely vaccinated compared to household incomes ≥$150,000 (95% CI: 10.1 to 26.7). Racialized parents reported greater unwillingness to vaccinate vs. White parents (aPD = 10.3; 95% CI: 1.5, 19.1). Vaccine-eligible adolescents from the most deprived neighbourhood were half as likely to be vaccinated compared to those from the least deprived neighbourhood (aPR = 0.48; 95% CI: 0.18 to 0.77).

INTERPRETATION

This study identified marked social inequalities in COVID-19 vaccine acceptance and uptake for children and adolescents. Efforts are needed to reach disadvantaged and marginalized populations with tailored strategies that promote informed decision making and facilitate access to vaccination.

摘要

背景

当前和未来针对儿童和青少年的 COVID-19 疫苗接种活动的成功在一定程度上取决于家长对疫苗接种的接受意愿。本研究调查了父母对儿童和青少年 COVID-19 疫苗接种的接受和接种情况的社会决定因素。

方法

我们使用了加拿大蒙特利尔正在进行的 COVID-19 队列研究的横断面数据,纳入了所有在 2021 年 5 月 18 日至 6 月 26 日期间完成在线问卷调查的 2 至 18 岁儿童的父母(n=809)。我们根据父母的教育程度、种族/族裔、出生地、家庭收入和社区计算了疫苗接种接受情况的儿童年龄调整患病率估计值,并使用多变量逻辑回归估计了调整后的患病率差异(aPD)和比值(aPR)。我们还检查了 12 至 18 岁疫苗接种合格样本(n=306)的疫苗接种率的社会决定因素。

结果

只有 12.4%的父母表示不太可能为孩子接种 COVID-19 疫苗,这表明家长对为孩子接种 COVID-19 疫苗的意愿较高。有年幼子女的父母更不愿意接种疫苗,收入较低的家庭、种族化群体和在加拿大境外出生的父母也是如此。家庭年收入<100,000 加元的儿童接种/极有可能接种疫苗的比例比家庭年收入≥150,000 加元的儿童低 18.4%(95%CI:10.1 至 26.7)。与白人父母相比,种族化父母表示更不愿意接种疫苗(aPD=10.3;95%CI:1.5,19.1)。来自最贫困社区的有资格接种疫苗的青少年接种疫苗的可能性是来自最不贫困社区的青少年的一半(aPR=0.48;95%CI:0.18 至 0.77)。

结论

本研究发现,儿童和青少年对 COVID-19 疫苗的接受和接种存在明显的社会不平等。需要努力通过有针对性的策略,向弱势群体和边缘化群体提供信息,促进知情决策,并便利疫苗接种。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae3/8573666/61186a056807/gr1_lrg.jpg

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