Waltereit Johanna, Czieschnek Charlotte, Albertowski Katja, Roessner Veit, Waltereit Robert
Department of Child and Adolescent Psychiatry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Department of Child and Adolescent Psychiatry, University Medical Center Göttingen, Göttingen, Germany.
Front Psychiatry. 2021 Oct 26;12:703023. doi: 10.3389/fpsyt.2021.703023. eCollection 2021.
Diagnosis of autism spectrum disorder (ASD) can be made early in childhood, but also later in adolescence or adulthood. In the latter cases, concerns about an individual's behavior typically lead to consultation of a mental health professional (MHP). As part of the initial clinical examination by the MHP, a clinical diagnostic interview is performed, in order to obtain the patient's history, and may lead to the hypothesis of ASD. We were here interested to study family and developmental history as key parts of the patient's history. The aim of the study was to investigate empirical differences between adolescents with ASD and adolescent control persons in family and developmental history. Clinical diagnostic interview items addressing family and developmental history were adopted from their regular use at several university hospitals and in leading textbooks. Parents of male adolescents with normal intelligence and an ASD diagnosis ( = 67) and parents of male adolescents without psychiatric diagnosis ( = 51) between the age of 12 and 17 years were investigated. Data were operationalized into three categories: 0 = normal behavior, 1 = minor pathological behavior, and 2 = major pathological behavior. Differences were analyzed by multiple -test of two-way ANOVA. Adolescents with ASD expressed a profile of items significantly differing from control persons. Comparison of significant items with the empirical ASD literature indicated robust accordance. Our findings support the importance and feasibility of the clinical diagnostic interview of family and developmental history for initiation of the diagnostic process of ASD in adolescents.
自闭症谱系障碍（ASD）的诊断可以在儿童早期做出，但也可能在青少年期或成年期较晚的时候做出。在后一种情况下，对个体行为的担忧通常会促使其咨询心理健康专业人员（MHP）。作为MHP初始临床检查的一部分，会进行临床诊断访谈，以获取患者的病史，并可能得出ASD的假设。我们在此感兴趣的是研究家庭和发育史作为患者病史的关键部分。该研究的目的是调查患有ASD的青少年与青少年对照人群在家庭和发育史上的实证差异。涉及家庭和发育史的临床诊断访谈项目取自几家大学医院的常规使用情况以及主要教科书。对年龄在12至17岁之间、智力正常且被诊断为ASD的男性青少年的父母（n = 67）以及无精神疾病诊断的男性青少年的父母（n = 51）进行了调查。数据被归纳为三类：0 = 正常行为，1 = 轻微病理行为，2 = 严重病理行为。通过双向方差分析的多重检验来分析差异。患有ASD的青少年表现出与对照人群有显著差异的项目特征。将显著项目与ASD实证文献进行比较，结果显示高度一致。我们的研究结果支持了对家庭和发育史进行临床诊断访谈对于启动青少年ASD诊断过程的重要性和可行性。
