Hoppenbrouwers P M, Driessens F C, Borggreven J M
J Dent Res. 1987 Aug;66(8):1370-4. doi: 10.1177/00220345870660081701.
Intact roots of human molars, which had not been exposed to the oral environment, were exposed to buffer solutions of pH 5.5, which contained, besides calcium and phosphate, various concentrations of fluoride. Densitometric measurements on contact-microradiograms of transverse sections of these roots produced data which were used to calculate the rate of demineralization (Vdem). Vdem appeared to be reduced with increasing fluoride concentration and with decreasing pIOHA (i.e., the negative logarithm of the ionic product of hydroxyapatite) of the buffer solution. In addition, it was observed that, after some days of exposure, remineralization started to occur within the surface layer at some micron from the outer surface and that the region within which remineralization took place was extended inward with increasing time of exposure. These data suggest that fluoride is effective in the prevention of root surface caries. The mechanism of the interaction of fluoride with the root mineral is discussed.
将未暴露于口腔环境的完整人类磨牙牙根暴露于pH 5.5的缓冲溶液中，该溶液除了含有钙和磷酸盐外，还含有不同浓度的氟化物。对这些牙根横切面的接触式微射线照片进行密度测量，得出的数据用于计算脱矿速率（Vdem）。随着氟化物浓度的增加以及缓冲溶液的pIOHA（即羟基磷灰石离子积的负对数）的降低，Vdem似乎会降低。此外，观察到，暴露几天后，在距外表面几微米的表层内开始发生再矿化，并且随着暴露时间的增加，发生再矿化的区域向内扩展。这些数据表明氟化物在预防牙根面龋方面是有效的。本文讨论了氟化物与牙根矿物质相互作用的机制。
