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Single-cell transcriptomic atlas of blood and lung from mice infected with SARS-CoV-2 revealing distinct virulence characteristics between prototype and Omicron BA.1 strain.感染新冠病毒的小鼠血液和肺部单细胞转录组图谱揭示了原始毒株和奥密克戎BA.1毒株之间不同的毒力特征。
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Inflammatory factor CCL2 enhances the interaction between monocyte-macrophage cells and liver parenchymal cells to promote liver inflammation and fibrosis in biliary atresia.炎症因子CCL2增强单核巨噬细胞与肝实质细胞之间的相互作用,以促进胆道闭锁中的肝脏炎症和纤维化。
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A novel mast cell marker gene-related prognostic signature to predict prognosis and reveal the immune landscape in head and neck squamous cell carcinoma.一种用于预测头颈部鳞状细胞癌预后并揭示其免疫格局的新型肥大细胞标志物基因相关预后特征。
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KDDC: a new framework that integrates kmers, dataset filtering, dimension reduction and classification algorithms to achieve immune cell heterogeneity classification.KDDC:一种整合k-mer、数据集过滤、降维和分类算法以实现免疫细胞异质性分类的新框架。
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Single-cell RNA sequencing dissects the immunosuppressive signatures in Helicobacter pylori-infected human gastric ecosystem.单细胞RNA测序剖析幽门螺杆菌感染的人类胃生态系统中的免疫抑制特征。
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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.新冠病毒感染肝脏的单核和空间转录组图谱揭示了患者肝脏的拓扑结构、功能及再生方面的器官破坏。
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COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas.

作者信息

Ren Xianwen, Wen Wen, Fan Xiaoying, Hou Wenhong, Su Bin, Cai Pengfei, Li Jiesheng, Liu Yang, Tang Fei, Zhang Fan, Yang Yu, He Jiangping, Ma Wenji, He Jingjing, Wang Pingping, Cao Qiqi, Chen Fangjin, Chen Yuqing, Cheng Xuelian, Deng Guohong, Deng Xilong, Ding Wenyu, Feng Yingmei, Gan Rui, Guo Chuang, Guo Weiqiang, He Shuai, Jiang Chen, Liang Juanran, Li Yi-Min, Lin Jun, Ling Yun, Liu Haofei, Liu Jianwei, Liu Nianping, Liu Shu-Qiang, Luo Meng, Ma Qiang, Song Qibing, Sun Wujianan, Wang GaoXiang, Wang Feng, Wang Ying, Wen Xiaofeng, Wu Qian, Xu Gang, Xie Xiaowei, Xiong Xinxin, Xing Xudong, Xu Hao, Yin Chonghai, Yu Dongdong, Yu Kezhuo, Yuan Jin, Zhang Biao, Zhang Peipei, Zhang Tong, Zhao Jincun, Zhao Peidong, Zhou Jianfeng, Zhou Wei, Zhong Sujuan, Zhong Xiaosong, Zhang Shuye, Zhu Lin, Zhu Ping, Zou Bin, Zou Jiahua, Zuo Zengtao, Bai Fan, Huang Xi, Zhou Penghui, Jiang Qinghua, Huang Zhiwei, Bei Jin-Xin, Wei Lai, Bian Xiu-Wu, Liu Xindong, Cheng Tao, Li Xiangpan, Zhao Pingsen, Wang Fu-Sheng, Wang Hongyang, Su Bing, Zhang Zheng, Qu Kun, Wang Xiaoqun, Chen Jiekai, Jin Ronghua, Zhang Zemin

出版信息

Cell. 2021 Nov 11;184(23):5838. doi: 10.1016/j.cell.2021.10.023.

DOI:10.1016/j.cell.2021.10.023
PMID:34767776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8582084/
Abstract
摘要