Lacour Philipp, Dang Phi Long, Heinzel Frank R, Parwani Abdul Shokor, Bähr Felix, Kucher Andreas, Hohendanner Felix, Niendorf Thoralf, Rahimi Faezeh, Saha Nandita, Han Haopeng, Rubarth Kerstin, Sherif Mohammad, Boldt Leif-Hendrik, Pieske Burkert, Blaschke Florian
Department of Internal Medicine and Cardiology, Charité-Universitaetsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.
Department of Internal Medicine and Cardiology, Charité-Universitaetsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
Heart Rhythm. 2022 Mar;19(3):372-380. doi: 10.1016/j.hrthm.2021.11.010. Epub 2021 Nov 10.
Recent case reports and small studies have reported activation of the magnet-sensitive switches in cardiovascular implantable electronic devices (CIEDs) by the new iPhone 12 series, initiating asynchronous pacing in pacemakers and suspension of antitachycardia therapies in implantable cardioverter-defibrillators (ICDs).
The purpose of this prospective single-center observational study was to quantify the risk of magnetic field interactions of the iPhone 12 with CIEDs.
A representative model of each CIED series from all manufacturers was tested ex vivo. Incidence and minimum distance necessary for magnet mode triggering were analyzed in 164 CIED patients with either the front or the back of the phone facing the device. The magnetic field of the iPhone 12 was analyzed using a 3-axis Hall probe.
Ex vivo, magnetic interference occurred in 84.6% with the back compared to 46.2% with the front of the iPhone 12 facing the CIED. In vivo, activation of the magnet-sensitive switch occurred in 30 CIED patients (18.3%; 21 pacemaker, 9 ICD) when the iPhone 12 was placed in close proximity over the CIED pocket and the back of the phone was facing the skin. Multiple binary logistic regression analysis identified implantation depth (95% confidence interval 0.02-0.24) as an independent predictor of magnet-sensitive switch activation.
Magnetic field interactions occur only in close proximity and with precise alignment of the iPhone 12 and CIEDs. It is important to advise CIED patients to not put the iPhone 12 directly on the skin above the CIED. Further recommendations are not necessary.
近期的病例报告和小型研究表明，新款iPhone 12系列手机会激活心血管植入式电子设备（CIED）中的磁敏开关，从而引发起搏器的异步起搏，并使植入式心律转复除颤器（ICD）的抗心动过速治疗暂停。
这项前瞻性单中心观察性研究的目的是量化iPhone 12与CIED之间磁场相互作用的风险。
对所有制造商的每个CIED系列的代表性模型进行体外测试。分析了164名CIED患者在手机正面或背面朝向设备时磁模式触发的发生率和所需的最小距离。使用三轴霍尔探头分析iPhone 12的磁场。
在体外，当iPhone 12背面朝向CIED时，84.6%的情况会发生磁干扰，而正面朝向CIED时为46.2%。在体内，当iPhone 12靠近CIED口袋放置且手机背面朝向皮肤时，30名CIED患者（18.3%；21名起搏器患者，9名ICD患者）的磁敏开关被激活。多元二元逻辑回归分析确定植入深度（95%置信区间0.02 - 0.24）是磁敏开关激活的独立预测因素。
磁场相互作用仅在iPhone 12与CIED紧密靠近且精确对齐时才会发生。建议CIED患者不要将iPhone 12直接放在CIED上方的皮肤上，这一点很重要。无需进一步的建议。
