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灰鼠狐猴(Microcebus murinus)作为早期灵长类脑进化的模型。

The gray mouse lemur (Microcebus murinus) as a model for early primate brain evolution.

机构信息

University of Geneva, Department of Basic Neurosciences, Rue Michel Servet 1, 1206 Geneva, Switzerland.

Verhaltensökologie und Soziobiologie, Deutsches Primatenzentrum, Kellnerweg 4, 37077 Göttingen, Germany; Leibniz Science Campus 'Primate Cognition', 37077 Göttingen, Germany.

出版信息

Curr Opin Neurobiol. 2021 Dec;71:92-99. doi: 10.1016/j.conb.2021.09.012. Epub 2021 Nov 9.

Abstract

The gray mouse lemur (Microcebus murinus), one of the world's smallest primates, is thought to share a similar ecological niche and many anatomical traits with early euprimates. As a result, it has been considered a suitable model system for early primate physiology and behavior. Moreover, recent studies have demonstrated that mouse lemurs have comparable cognitive abilities and cortical functional organization as haplorhines. Finally, the small brain size of mouse lemurs provides us with actual lower limits for miniaturization of functional brain circuits within the primate clade. Considering its phylogenetic position and early primate-like traits, the mouse lemurs are a perfect model species to study the early evolution of primate brains.

摘要

灰鼠狐猴(Microcebus murinus)是世界上最小的灵长类动物之一,被认为与早期真兽类具有相似的生态位和许多解剖特征。因此,它被认为是研究早期灵长类动物生理和行为的合适模型系统。此外,最近的研究表明,鼠狐猴具有与原猴类相当的认知能力和皮质功能组织。最后,鼠狐猴的小大脑尺寸为我们提供了灵长类动物中功能脑回路缩小的实际下限。考虑到其系统发育位置和早期类似真兽类的特征,鼠狐猴是研究灵长类动物大脑早期进化的理想模式物种。

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