Kiss I, Deák F, Mestrić S, Delius H, Soos J, Dékány K, Argraves W S, Sparks K J, Goetinck P F
Proc Natl Acad Sci U S A. 1987 Sep;84(18):6399-403. doi: 10.1073/pnas.84.18.6399.
The structure of the chicken link protein gene has been determined from a series of genomic clones that cover the entire coding region as well as the complete 3'-untranslated region and a small portion of the 5'-untranslated region. The gene is greater than 80 kilobase pairs long and is present in a single copy in the chicken genome. The link protein gene contains at least five exons with four encoding the entire protein. The domain of link protein that has homologies with immunoglobulin-like proteins and the tandemly repeated hyaluronic acid binding domains are each encoded by separate exons. The exon-intron structure indicates that the link protein gene may have arisen by exon duplication and exon shuffling.
鸡连接蛋白基因的结构已通过一系列基因组克隆确定，这些克隆覆盖了整个编码区以及完整的3'-非翻译区和一小部分5'-非翻译区。该基因长度超过80千碱基对，在鸡基因组中以单拷贝形式存在。连接蛋白基因至少包含五个外显子，其中四个编码整个蛋白质。与免疫球蛋白样蛋白具有同源性的连接蛋白结构域和串联重复的透明质酸结合结构域分别由单独的外显子编码。外显子-内含子结构表明，连接蛋白基因可能是通过外显子重复和外显子重排产生的。
