Arahman Nasrul, Rosnelly Cut Meurah, Yusni Yusni, Fahrina Afrillia, Silmina Silmina, Ambarita Aulia Chintia, Bilad Muhammad Roil, Gunawan Poernomo, Rajabzadeh Saeid, Takagi Ryosuke, Matsuyama Hideto, Aziz Muhammad
Department of Chemical Engineering, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Magister Program of Environmental Management, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Polymers (Basel). 2021 Oct 21;13(21):3632. doi: 10.3390/polym13213632.
α-Lactalbumin is an essential protein with multiple roles in physiological and the nutritional functionalities, such as diabetic prevention, blood pressure stabilization, and cancer cell inhibition. In the present work, polyethersulfone (PES)-based membranes were developed by incorporating Pluronic F127 and carbon nanotubes with single- and multi-walled dimensions (Sw-Cnts and Mw-Cnts) as additives. The resulting membranes were evaluated for use in the filtration of α-lactalbumin protein solution. Four series of membranes, including PES pristine membrane, were fabricated via the phase inversion process. The characteristics of the membrane samples were analyzed in terms of morphology, membrane surface hydrophilicity and roughness, and surface chemistry. The characterization results show that the incorporation of additive increased the surface wettability by reducing the surface water contact angle from 80.4° to 64.1° by adding F127 and Mw-Cnt additives. The highest pure water permeability of 135 L/(m·h·bar) was also exhibited by the PES/F127/Mw-Cnt membrane. The performance of the modified membranes was clearly better than the pristine PSF for α-lactalbumin solution filtration. The permeability of α-lactalbumin solution increased from 9.0 L/(m·h·bar) for the pristine PES membrane to 10.5, 11.0 and 11.5 L/(m·h·bar) for membranes loaded with Pluronic F127, Sw-Cnts, and Mw-Cnts, respectively. Those increments corresponded to 17, 22, and 28%. Such increments could be achieved without altering the α-lactalbumin rejections of 80%. Remarkably, the rejection for the membrane loaded with Sw-Cnts even increased to 89%.
α-乳白蛋白是一种必需蛋白质，在生理和营养功能方面具有多种作用，如预防糖尿病、稳定血压和抑制癌细胞。在本研究中，通过将Pluronic F127和具有单壁和多壁尺寸的碳纳米管（单壁碳纳米管和多壁碳纳米管）作为添加剂加入，制备了聚醚砜（PES）基膜。对所得膜进行了α-乳白蛋白蛋白溶液过滤性能的评估。通过相转化法制备了包括PES原始膜在内的四个系列的膜。从膜的形态、表面亲水性和粗糙度以及表面化学等方面对膜样品的特性进行了分析。表征结果表明，添加添加剂通过加入F127和多壁碳纳米管添加剂将表面水接触角从80.4°降低到64.1°，从而提高了表面润湿性。PES/F127/多壁碳纳米管膜还表现出最高的纯水通量，为135 L/(m·h·bar)。在α-乳白蛋白溶液过滤方面，改性膜的性能明显优于原始聚砜膜。α-乳白蛋白溶液的通量从原始PES膜的9.0 L/(m·h·bar)分别增加到负载Pluronic F127、单壁碳纳米管和多壁碳纳米管的膜的10.5、11.0和11.5 L/(m·h·bar)。这些增量分别对应17%、22%和28%。在不改变α-乳白蛋白截留率80%的情况下可实现这种增量。值得注意的是，负载单壁碳纳米管的膜的截留率甚至提高到了89%。
