Hairfield W M, Warren D W, Hinton V A, Seaton D L
Dental Research Center, University of North Carolina at Chapel Hill.
Cleft Palate J. 1987 Jul;24(3):183-9.
The purpose of the present study was to assess quantitatively the nasal valve area during normal inspiratory and expiratory maneuvers. The pressure-flow technique of Warren was used to estimate nasal size in 15 adult subjects who had no previous history of nasal surgery or abnormality. Cross-sectional size of the nasal airway was also assessed (1) after insertion of tubing to eliminate alar effects, (2) after administration of 0.1% Otrivin decongestant to eliminate mucosal effects, and (3) by blocking each nostril individually. Mean areas of 0.63 cm2 +/- 0.17 during inspiration and 0.56 cm2 +/- 0.14 during expiration. This difference is statistically significant (less than 0.01) and the effect was maintained under conditions of occlusion of either nostril, insertion of tubing, and administration of Otrivin. These findings suggest that the nasal valve acts as a respiratory brake during expiration possibly to allow adequate time for gas exchange at the alveoli.
本研究的目的是定量评估正常吸气和呼气动作时的鼻瓣区面积。采用沃伦的压力-流量技术对15名既往无鼻手术史或鼻腔异常的成年受试者的鼻腔大小进行评估。还评估了鼻气道的横截面积:(1) 插入导管以消除鼻翼影响后;(2) 给予0.1%羟甲唑啉减充血剂以消除黏膜影响后;(3) 分别堵塞每个鼻孔后。吸气时平均面积为0.63平方厘米±0.17,呼气时平均面积为0.56平方厘米±0.14。这种差异具有统计学意义(小于0.01),并且在堵塞任一鼻孔、插入导管和给予羟甲唑啉的情况下该效应均持续存在。这些发现表明,鼻瓣在呼气时起到呼吸制动器的作用,可能是为了在肺泡进行气体交换留出足够时间。