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Wild-type APC Influences the Severity of Familial Adenomatous Polyposis.

作者信息

Flisikowski Krzysztof, Perleberg Carolin, Niu Guanglin, Winogrodzki Thomas, Bak Agnieszka, Liang Wei, Grodziecki Alessandro, Zhang Yue, Pausch Hubert, Flisikowska Tatiana, Klinger Bernhard, Perkowska Anna, Kind Alexander, Switonski Marek, Janssen Klaus-Peter, Saur Dieter, Schnieke Angelika

机构信息

Livestock Biotechnology, School of Life Sciences, Technical University of Munich, Munich, Germany.

Livestock Biotechnology, School of Life Sciences, Technical University of Munich, Munich Germany; Center of Integrated Protein Science Munich, Division of Clinical Pharmacology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

出版信息

Cell Mol Gastroenterol Hepatol. 2022;13(2):669-671.e3. doi: 10.1016/j.jcmgh.2021.11.002. Epub 2021 Nov 10.

DOI:10.1016/j.jcmgh.2021.11.002
PMID:34774804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8777002/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/f9afbb582086/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/da30bbb9e0ad/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/6064b2001981/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/f8c5e433d2e9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/968dd496f1b7/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/f9afbb582086/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/da30bbb9e0ad/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/6064b2001981/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/f8c5e433d2e9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/968dd496f1b7/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28c/8777002/f9afbb582086/fx3.jpg

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本文引用的文献

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Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis.胆汁酸-微生物群互作对胃肠道炎症和癌变的影响。
Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):111-128. doi: 10.1038/nrgastro.2017.119. Epub 2017 Oct 11.
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Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression.猪家族性腺瘤病模型使腺瘤进展早期事件的系统分析成为可能。
Sci Rep. 2017 Jul 26;7(1):6613. doi: 10.1038/s41598-017-06741-8.
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A porcine model of familial adenomatous polyposis.家族性腺瘤性息肉病的猪模型。
Identification of driving genes of familial adenomatous polyposis by differential gene expression analysis and weighted gene co-expression network analysis.
通过差异基因表达分析和加权基因共表达网络分析鉴定家族性腺瘤性息肉病的驱动基因。
Technol Health Care. 2024;32(3):1675-1696. doi: 10.3233/THC-230719.
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Elevated circulating Hsp70 levels are correlative for malignancies in different mammalian species.循环 HSP70 水平升高与不同哺乳动物物种的恶性肿瘤相关。
Cell Stress Chaperones. 2023 Jan;28(1):105-118. doi: 10.1007/s12192-022-01311-y. Epub 2022 Nov 18.
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APC and its modifiers in colon cancer.APC 及其在结肠癌中的修饰物。
Adv Exp Med Biol. 2009;656:85-106. doi: 10.1007/978-1-4419-1145-2_8.
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Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes.家族性腺瘤性息肉病的变异解释:基因型与表型的关系及修饰基因的证据
Gut. 2002 Sep;51(3):420-3. doi: 10.1136/gut.51.3.420.
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Small changes in expression affect predisposition to tumorigenesis.表达上的微小变化会影响肿瘤发生的易感性。
Nat Genet. 2002 Jan;30(1):25-6. doi: 10.1038/ng799. Epub 2001 Dec 17.
7
Apoptosis and APC in colorectal tumorigenesis.细胞凋亡与腺瘤性息肉病基因在结直肠癌发生中的作用
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