Servei de Cirurgia Vascular, Hospital Universitari de Tarragona Joan XXIII, Tarragona, Catalunya, Spain.
Servei de Cirurgia Vascular, Hospital Universitari de Tarragona Joan XXIII, Tarragona, Catalunya, Spain.
Ann Vasc Surg. 2022 Mar;80:392.e1-392.e6. doi: 10.1016/j.avsg.2021.09.023. Epub 2021 Nov 11.
Ergotism is an uncommon condition that affects patients with exposure to ergot alkaloids causing ischemia of extremities. We report the case of lower extremities ischemia caused by ergot toxicity in a human immunodeficiency virus (HIV) positive individual due to the interaction between ergot alkaloid and Cobicistat. In addition, we present a brief review of medical, and pharmacological aspects of this condition. To our knowledge, this is the second reported case describing this interaction.
麦角中毒是一种罕见的疾病，会影响接触麦角生物碱的患者，导致四肢缺血。我们报告了一例人类免疫缺陷病毒（HIV）阳性个体因麦角生物碱与考比司他相互作用而导致的下肢缺血的病例。此外，我们还简要回顾了这种情况的医学和药理学方面。据我们所知，这是第二个描述这种相互作用的报告病例。
