Department of Health Sciences, School of Sciences, European University Cyprus, Nicosia 1516, Cyprus.
University of West Attica, Department of Physiotherapy, Laboratory of Neuromuscular and Cardiovascular Study of Motion, Athens, Greece.
J Bodyw Mov Ther. 2021 Oct;28:246-254. doi: 10.1016/j.jbmt.2021.06.003. Epub 2021 Jun 12.
Complete rupture of the anterior cruciate ligament is a major problem owing to inadequate surgery outcomes and the limited healing capacity of the ligament. This study aimed to summarise the evidence on the spontaneous healing potential of the anterior cruciate ligament in terms of fiber continuity based on magnetic resonance imaging (MRI) findings.
PubMed, Cochrane Library, Scopus, and MEDLINE databases were searched from their inception to November 1, 2020. Studies that analysed patients diagnosed with complete anterior cruciate ligament rupture were included. Further, studies that used conservative treatment as intervention and MRI finding as an outcome measure were included.
In total, 9 studies, with a total of 734 participants, met the inclusion criteria. Knee laxity was measured in all studies. Two studies classified patients according to rupture location, where most ligaments with restored fiber continuity had proximal ruptures. All included studies reported spontaneous healing. Furthermore, none of the included studies reported the absence of healing.
This systematic review demonstrates the intrinsic healing capacity of the anterior cruciate ligament, indicating a higher healing potential for proximal ruptures. While our study reveals an emerging need to question general practice, a definitive conclusion could not be drawn owing to the low quality of the studies included and the heterogeneity of results.
由于手术效果不理想和韧带愈合能力有限,前交叉韧带完全断裂是一个主要问题。本研究旨在根据磁共振成像(MRI)结果,总结前交叉韧带纤维连续性方面的自然愈合潜力的证据。
从数据库建立到 2020 年 11 月 1 日,检索了 PubMed、Cochrane 图书馆、Scopus 和 MEDLINE 数据库。纳入分析诊断为完全前交叉韧带断裂患者的研究。此外,还纳入了使用保守治疗作为干预措施和 MRI 结果作为结局指标的研究。
共有 9 项研究,总计 734 名参与者,符合纳入标准。所有研究均测量了膝关节松弛度。有 2 项研究根据断裂位置对患者进行了分类,其中大多数纤维连续性恢复的韧带都有近端断裂。所有纳入的研究均报告了自发性愈合。此外,没有纳入的研究报告了愈合缺失。
本系统评价表明前交叉韧带具有内在的愈合能力,表明近端断裂具有更高的愈合潜力。虽然我们的研究揭示了对一般实践提出质疑的必要性,但由于纳入研究的质量较低和结果存在异质性,无法得出明确的结论。