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子宫输卵管造影术与腹腔镜检查在女性输卵管性不孕诊断中的比较

Comparison of Hysterosalpingography With Laparoscopy in the Diagnosis of Tubal Factor of Female Infertility.

作者信息

Tan Jifan, Deng Min, Xia Meng, Lai Muhua, Pan Wenwei, Li Yubin

机构信息

Reproductive Medicine Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Guangdong Provincial Key Laboratory of Reproductive Medicine, Guangzhou, China.

出版信息

Front Med (Lausanne). 2021 Oct 29;8:720401. doi: 10.3389/fmed.2021.720401. eCollection 2021.

Abstract

Laparoscopy is considered to be the gold standard in the evaluation of causes leading to infertility. Hysterosalpingography (HSG) permits indirect visualization of the cervical canal, uterine cavity, and tube patency, which is helpful for evaluating the causes of infertility. This study aimed to detect tubal abnormalities in infertile women by HSG or laparoscopy and determine the value of HSG in diagnosing fallopian tube status. The study group consisted of 1,276 patients. HSG was performed as a preliminary test for the evaluation of fallopian tube status. Women were subjected to laparoscopic examination on evidence of HSG abnormalities. The negative predictive value of HSG for detecting patency or occlusion for the right/left tube was 92.08 and 95.44%, respectively. The kappa values for the consistent diagnosis in the right/left tube were 0.470 and 0.574, respectively. In cases of low patency of the right/left tube, there was a greater than a 40% chance for the tube to be patent, and the remaining high probability was pelvic adhesion. The positive predictive value of HSG for detecting patency or occlusion for both tubes was 87.2%. The kappa value was 0.898 [95% CI (0.838, 0.937), < 0.001], which meant that the diagnostic accuracy of HSG for both tube patency/occlusion was explicit. The kappa value for the diagnosis of hydrosalpinx (especially for bilateral tube hydrosalpinx) was 0.838 [95% CI (0.754, 0.922), < 0.001], and the diagnostic accuracy for HSG was 79.8, 67.9, and 72.4%, respectively. The current study concluded that HSG is a good diagnostic modality to detect tube abnormalities in infertile patients. HSG and laparoscopy are complementary to each other and whenever the patient is undertaken for diagnosis of infertility. Cost-effective HSG had good predictive value in identifying tubal factor infertility.

摘要

腹腔镜检查被认为是评估导致不孕原因的金标准。子宫输卵管造影术(HSG)可间接观察宫颈管、子宫腔和输卵管通畅情况,有助于评估不孕原因。本研究旨在通过HSG或腹腔镜检查检测不孕女性的输卵管异常,并确定HSG在诊断输卵管状况方面的价值。研究组由1276例患者组成。HSG作为评估输卵管状况的初步检查。对HSG异常的女性进行腹腔镜检查。HSG检测右侧/左侧输卵管通畅或阻塞的阴性预测值分别为92.08%和95.44%。右侧/左侧输卵管一致诊断的kappa值分别为0.470和0.574。在右侧/左侧输卵管通畅度较低的情况下,输卵管通畅的可能性大于40%,其余高概率为盆腔粘连。HSG检测双侧输卵管通畅或阻塞的阳性预测值为87.2%。kappa值为0.898[95%CI(0.838,0.937),<0.001],这意味着HSG对双侧输卵管通畅/阻塞的诊断准确性明确。诊断输卵管积水(尤其是双侧输卵管积水)的kappa值为0.838[95%CI(0.754,0.922),<0.001],HSG的诊断准确性分别为79.8%、67.9%和72.4%。本研究得出结论,HSG是检测不孕患者输卵管异常的良好诊断方法。HSG和腹腔镜检查相互补充,无论何时对患者进行不孕诊断。具有成本效益的HSG在识别输卵管因素性不孕方面具有良好的预测价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f5e/8585930/ddc3e668503c/fmed-08-720401-g0001.jpg

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