Sandra V Kala Vani, Shaik Ziauddhin, Simhadri Geetika, Obili Govindu Gari Lakshmikar Reddy, Siddamreddy Bindu Priya, Makem Naveen
Department of Orthodontics and Dentofacial Orthopedics, C.K.S. Teja Institute of Dental Sciences and Research, Chadalawada Nagar, Renigunta Road, Tirupathi, Andhra Pradesh, India.
Department of Orthodontics and Dentofacial Orthopedics, Coorg Institute of Dental Sciences, Kodagu, Coorg District, Virajpet, Karnataka, India.
J Clin Transl Res. 2021 Sep 27;7(5):625-630. eCollection 2021 Oct 26.
There is an increased prevalence of oral ailments such as dental caries, gingivitis, and periodontitis when orthodontic therapy is administered. Poor oral hygiene in conjunction with the placement of fixed orthodontic appliances is considered a significant factor in raising accumulation of bacterial plaque and its associated inflammatory response.
The present study aimed to evaluate and compare laser therapy with subgingival irrigation using ozonated water on gingivitis in patients undergoing fixed orthodontic treatment and to ascertain the presence of the inflammatory marker monocyte chemoattractant protein (MCP-1) in gingival crevicular fluid (GCF).
This study was a double-blind clinical study in which a split-mouth design was applied in 30 subjects for 28 days that received fixed orthodontic therapy. In each subject, the upper right quadrant (control side) was irrigated with 0.01 mg/L ozonated water and the upper left quadrant (experimental side) was irradiated with a diode laser on day 0 (baseline) and day 7. The patients were recalled on days 7, 14, and 28 and clinical parameters were recorded at each visit. Biochemical evaluation of gingival inflammation with MCP-1 levels in GCF was obtained at the baseline (day 0) and on day 28.
A statistically significant (p < 0.05) reduction of all clinical parameters and MCP-1 activity in GCF was observed on both sides. Low-level laser irradiation showed a significant reduction of clinical parameters and MCP-1 activity compared to subgingival ozone irrigation.
Laser therapy can be considered a more effective method than subgingival ozone irrigation in patients undergoing fixed orthodontic treatment as it showed a consistent improvement in gingival inflammation.
Fixed orthodontic appliances make oral hygiene maintenance difficult and results in gingivitis. Adjunctive oral hygiene procedures such as subgingival irrigation with ozonated water or laser irradiation are beneficial. The data from this study suggest that irrigation with ozonated water or laser irradiation reduces gingival inflammation, with laser therapy being more effective.
在进行正畸治疗时，龋齿、牙龈炎和牙周炎等口腔疾病的患病率会增加。口腔卫生不良与固定正畸矫治器的放置被认为是导致细菌菌斑积聚及其相关炎症反应增加的重要因素。
本研究旨在评估和比较激光治疗与使用臭氧水进行龈下冲洗对接受固定正畸治疗患者牙龈炎的疗效，并确定龈沟液（GCF）中炎症标志物单核细胞趋化蛋白（MCP-1）的存在情况。
本研究为双盲临床研究，采用裂嘴设计，对30名接受固定正畸治疗的受试者进行了为期28天的研究。在每个受试者中，右上象限（对照侧）在第0天（基线）和第7天用0.01 mg/L的臭氧水冲洗，左上象限（实验侧）用二极管激光照射。在第7、14和28天对患者进行回访，并在每次回访时记录临床参数。在基线（第0天）和第28天对GCF中MCP-1水平进行龈炎的生化评估。
两侧的所有临床参数和GCF中的MCP-1活性均有统计学意义的降低（p < 0.05）。与龈下臭氧冲洗相比，低水平激光照射显示临床参数和MCP-1活性有显著降低。
在接受固定正畸治疗的患者中，激光治疗可被认为是比龈下臭氧冲洗更有效的方法，因为它在牙龈炎症方面显示出持续改善。
固定正畸矫治器使口腔卫生维护变得困难，并导致牙龈炎。辅助口腔卫生程序，如用臭氧水进行龈下冲洗或激光照射是有益的。本研究数据表明，用臭氧水冲洗或激光照射可减轻牙龈炎症，激光治疗更有效。
