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Eltrombopag in adult patients with immune thrombocytopenia in the real-world in France, including off-label use before 6 months of disease duration: The multicenter, prospective ELEXTRA study.艾曲泊帕在法国真实世界中成年免疫性血小板减少症患者中的应用，包括疾病持续时间不足6个月时的超说明书用药：多中心前瞻性ELEXTRA研究
Am J Hematol. 2022 Feb 1;97(2):E40-E44. doi: 10.1002/ajh.26404. Epub 2021 Dec 6.
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Severe cutaneous toxicity related to Eltrombopag.与艾曲泊帕相关的严重皮肤毒性。
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Eltrombopag--an oral thrombopoietin agonist.艾曲波帕——一种口服促血小板生成素激动剂。
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Eltrombopag--a novel approach for the treatment of chronic immune thrombocytopenic purpura: review and safety considerations.艾曲波帕——治疗慢性免疫性血小板减少性紫癜的新方法：综述与安全性考量
Drug Des Devel Ther. 2010 Jul 21;4:139-45. doi: 10.2147/dddt.s8601.
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Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): a randomised, multicentre, placebo-controlled trial.依鲁替尼治疗儿童慢性免疫性血小板减少症（PETIT2）的随机、多中心、安慰剂对照试验。
Lancet. 2015 Oct 24;386(10004):1649-58. doi: 10.1016/S0140-6736(15)61107-2. Epub 2015 Jul 28.

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Real-world experience of thrombopoietin receptor agonists in pediatric immune thrombocytopenia: a report from a Chinese tertiary children's hospital.血小板生成素受体激动剂在儿童免疫性血小板减少症中的真实世界经验：来自中国一家三级儿童医院的报告。
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Use of thrombopoietin receptor agonists in adults with immune thrombocytopenia: a systematic review and Central European expert consensus.成人免疫性血小板减少症中血小板生成素受体激动剂的应用：系统评价和中欧专家共识。
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本文引用的文献

1
American Society of Hematology 2019 guidelines for immune thrombocytopenia.美国血液学会 2019 年免疫性血小板减少症治疗指南。
Blood Adv. 2019 Dec 10;3(23):3829-3866. doi: 10.1182/bloodadvances.2019000966.
2
Updated international consensus report on the investigation and management of primary immune thrombocytopenia.更新的原发性免疫性血小板减少症的调查和管理国际共识报告。
Blood Adv. 2019 Nov 26;3(22):3780-3817. doi: 10.1182/bloodadvances.2019000812.
3
Immune Thrombocytopenia.免疫性血小板减少症
N Engl J Med. 2019 Sep 5;381(10):945-955. doi: 10.1056/NEJMcp1810479.
4
Thrombopoietin receptor agonists: ten years later.血小板生成素受体激动剂：十年后。
Haematologica. 2019 Jun;104(6):1112-1123. doi: 10.3324/haematol.2018.212845. Epub 2019 May 9.
5
Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults.新诊断的成人免疫性血小板减少症患者出血的风险因素，包括血小板计数阈值。
J Thromb Haemost. 2018 Sep;16(9):1830-1842. doi: 10.1111/jth.14227. Epub 2018 Aug 12.
6
Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.成人及儿童免疫性血小板减少性紫癜术语、定义及疗效标准的标准化：国际工作组报告
Blood. 2009 Mar 12;113(11):2386-93. doi: 10.1182/blood-2008-07-162503. Epub 2008 Nov 12.

Eltrombopag in adult patients with immune thrombocytopenia in the real-world in France, including off-label use before 6 months of disease duration: The multicenter, prospective ELEXTRA study.

作者信息

Moulis Guillaume, Germain Johanne, Rueter Manuela, Lafaurie Margaux, Aroichane Myriam, Comont Thibault, Mahévas Matthieu, Viallard Jean-François, Chèze Stéphane, Ebbo Mikaël, Audia Sylvain, Leclerc-Teffahi Soraya, Sommet Agnès, Beyne-Rauzy Odile, Michel Marc, Godeau Bertrand, Lapeyre-Mestre Maryse

机构信息

Department of Internal Medicine, Toulouse University Hospital, Toulouse, France.

Clinical Investigation Center, Toulouse University Hospital, Toulouse, France.

出版信息

Am J Hematol. 2022 Feb 1;97(2):E40-E44. doi: 10.1002/ajh.26404. Epub 2021 Dec 6.

DOI:10.1002/ajh.26404
PMID:34779031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9300059/
Abstract
摘要